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Home / Primary Antibodies / Polyclonal Antibodies

ZBP1 Antibody (CSB-PA026311GA01HU)

BHA10549336
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Contact us to order
Tel
+1 866.986.9598
Email
[email protected]
Get a Quote
Ask Merchant
Request More Infos
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Antigen ZBP1
Uniprot Q9H171
Database Links

HGNC:16176

OMIM:606750

KEGG:hsa:81030

STRING:9606.ENSP00000360215

UniGene:Hs.302123
Function Participates in the detection by the host's innate immune system of DNA from viral, bacterial or even host origin. Plays a role in host defense against tumors and pathogens. Acts as a cytoplasmic DNA sensor which, when activated, induces the recruitment of TBK1 and IRF3 to its C-terminal region and activates the downstream interferon regulatory factor (IRF) and NF-kappa B transcription factors, leading to type-I interferon production. ZBP1-induced NF-kappaB activation probably involves the recruitment of the RHIM containing kinases RIPK1 and RIPK3 (By similarity).
Pathway Necroptosis
Tissue Specificity Highly expressed in lymphatic tissues including lymph node, leukocytes, tonsil, bone marrow and spleen. Expressed to a lesser extent in thymus, lung and liver.
Buffer PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20℃, Avoid freeze / thaw cycles.
Format Liquid
Purification Antigen Affinity Purified
Purity Antigen Affinity Purified
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Storage Buffer

PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
Applications ELISA, WB, IHC
Description ELISA ; WB ; IHC, WB ; ELISA ; IHC
Tested Application ELISA,WB,IHC
Datasheet
ELISA Protocol
Western Blotting(WB) Protocol
Immunohistochemistry (IHC) Protocol
SKU Supplier No. Size Your price Quantity
BHA10549336 CSB-PA026311GA01HU 100ul $600
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