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Home / Primary Antibodies / Polyclonal Antibodies

BIRC2 Antibody (CSB-PA002703GA01HU)

BHA10544050
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Tel
+1 866.986.9598
Email
[email protected]
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Antigen BIRC2
Target Details This protein is a member of a family of proteins that inhibits apoptosis by binding to tumor necrosis factor receptor-associated factors TRAF1 and TRAF2, probably by interfering with activation of ICE-like proteases. This encoded protein inhibits apoptosis induced by serum deprivation and menadione, a potent inducer of free radicals.
Uniprot Q13490
Database Links

HGNC:590

OMIM:601712

KEGG:hsa:329

STRING:9606.ENSP00000227758

UniGene:Hs.696238
Function Multi-functional protein which regulates not only caspases and apoptosis, but also modulates inflammatory signaling and immunity, mitogenic kinase signaling, and cell proliferation, as well as cell invasion and metastasis. Acts as an E3 ubiquitin-protein ligase regulating NF-kappa-B signaling and regulates both canonical and non-canonical NF-kappa-B signaling by acting in opposite directions
Pathway Hippo signaling pathway Focal adhesion NF-kappa B signaling pathway TNF signaling pathway Apoptosis Necroptosis Ubiquitin mediated proteolysis NOD-like receptor signaling pathway
Protein Families IAP family
Tissue Specificity Present in many fetal and adult tissues. Mainly expressed in adult skeletal muscle, thymus, testis, ovary, and pancreas, low or absent in brain and peripheral blood leukocytes.
Buffer PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20℃, Avoid freeze / thaw cycles.
Format Liquid
Purification Antigen Affinity Purified
Purity Antigen Affinity Purified
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Storage Buffer

PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
Applications ELISA, WB, IHC
Description ELISA ; WB ; IHC, WB ; ELISA ; IHC
Tested Application ELISA,WB,IHC
Datasheet
ELISA Protocol
Western Blotting(WB) Protocol
Immunohistochemistry (IHC) Protocol
SKU Supplier No. Size Your price Quantity
BHA10544050 CSB-PA002703GA01HU 100ul $600
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