Receptor for the MIP-3-beta chemokine. Probable mediator of EBV effects on B-lymphocytes or of normal lymphocyte functions.Ishiura N, et al. (2010)Eur J Immunol 40, 1192-204. Browne CD, et al. (2009) Immunity 31, 749-60. Aiba Y, et al. (2008)Blood 111, 1497-503.
Host
Rabbit
Immunogen
Peptide sequence around phosphorylation site of tyrosine 531 (D-S-Y(p)-E-N) derived from Human CD19.
Involvement In Disease
Immunodeficiency, common variable, 3 (CVID3)
Raised In
Rabbit
Reactivity
Human, Mouse
Regulatory
RUO
Relevance
Receptor for the MIP-3-beta chemokine. Probable mediator of EBV effects on B-lymphocytes or of normal lymphocyte functions.
Ishiura N, et al. (2010)Eur J Immunol 40, 1192-204. Browne CD, et al. (2009) Immunity 31, 749-60. Aiba Y, et al. (2008)Blood 111, 1497-503.
Species
Homo Sapiens (Human)
Specificity
The antibody detects endogenous level of CD19 only when phosphorylated at tyrosine 531.
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Format
liquid
Purification
Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi
Purity
Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.