ZAP-70 iFluor488 C-D12 IgG1,k (ASR)

Mfr.No.	4203112, 4203115
Antigen	Zap70
Clonality	Monoclonal
Description	The clone C-D12, a mouse monoclonal antibody selectively binds with the 70kd tyrosine phosphoprotein known as ZAP-70 which is usually associated with the ?-chain CD3-receptor-associated protein tyrosine kinase (PTK). It is a member of the Syk family that is localized exclusively to the cytosol of T cells and natural killer (NK) cells and is required for their cellular activation. It is generally considered the T-lymphocyte counterpart of Syk, a B-cell receptor (BCR)-associated kinase that belongs to the same PTK family and plays a similar role in the antigen receptor signaling in the B-lineage cells. It facilitates the upregulation of Fas ligand in activation-induced T cell apoptosis. ZAP-70 expression plays an important role in the clinical diagnosis of various types of hematologic malignancies.
Host	Mouse
Immunogen Region	Recombinant fragment of human ZAP70 protein (around aa 247-382)
Isotype	IgG1,k
Reactivity	Human

Product Manual	Datasheet MSDS

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Combination SKU	Supplier No.	Size	Your price	Quantity
BHA19901355-1	4203112	50 Test	$295		Add to Cart
BHA19901355-2	4203115	100 Test	$475		Add to Cart