• Alternative Names :
• Twinfilin-2 (A6-related protein) (hA6RP) (Protein tyrosine kinase 9-like) (Twinfilin-1-like protein), TWF2, PTK9L

• Categories :
• Primary Antibodies

• Clonality :
• polyclonal

• Description :
• Actin-binding protein involved in motile and morphological processes. Inhibits actin polymerization, likely by sequestering G-actin. By capping the barbed ends of filaments, it also regulates motility. Seems to play an important role in clathrin-mediated endocytosis and distribution of endocytic organelles. May play a role in regulating the mature length of the middle and short rows of stereocilia

• Host :
• Rabbit

• Immunogen :
• Recombinant Human Twinfilin-2 protein (1-349AA)

• Isotype :
• IgG

• Raised In :
• Rabbit

• Reactivity :
• Human

• Regulatory :
• RUO

• Relevance :
• Actin-binding protein involved in motile and morphological processes. Inhibits actin polymerization, likely by sequestering G-actin. By capping the barbed ends of filaments, it also regulates motility. Seems to play an important role in clathrin-mediated endocytosis and distribution of endocytic organelles. May play a role in regulating the mature length of the middle and short rows of stereocilia

• Species :
• Homo Sapiens (Human)

• Subcellular Location :
• Cytoplasm, cytoskeleton, Cytoplasm, perinuclear region, Cell projection, stereocilium

• Antigen :
• TWF2

• Uniprot :
• Q6IBS0

• Database Links :
• 
  

  HGNC:9621

  OMIM:607433

  KEGG:hsa:11344

  STRING:9606.ENSP00000303908

  UniGene:Hs.436439

• Function :
• Actin-binding protein involved in motile and morphological processes. Inhibits actin polymerization, likely by sequestering G-actin. By capping the barbed ends of filaments, it also regulates motility. Seems to play an important role in clathrin-mediated endocytosis and distribution of endocytic organelles. May play a role in regulating the mature length of the middle and short rows of stereocilia (By similarity).

• Protein Families :
• Actin-binding proteins ADF family, Twinfilin subfamily

• Research Area :
• Signal Transduction

• Tissue Specificity :
• Ubiquitously expressed (at protein level).

• Buffer :
• PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Form :
• Liquid

• Format :
• Liquid

• Purification :
• Antigen Affinity purified

• Purity :
• Antigen Affinity purified

• Storage :
• Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

• Storage Buffer :
• 
  
  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Datasheet :
• 

• ELISA Protocol :

• Western Blotting(WB) Protocol :

• Immunoprecipitation (IP) Protocol :