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Home / Antibodies

Anti-ITGB5 Antibody BHA11300358

SKU : BHA11300358

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Mfr.No.	BS1188
Alternative Names	Integrin beta-5 ; ITGB5
Antigen	ITGB5
Categories	Primary Antibodies
Chromosome Location	3q21.2
Clonality	polyclonal
Description	Integrins are heterodimers composed of noncovalently associated transmembrane α and β subunits. The 16α and 8β subunits heterodimerize to produce more than 20 different receptors. Most Integrin receptors bind ligands that are components of the extracellular matrix, including Fibronectin, Collagen and Vitronectin. Certain Integrins can also bind to soluble ligands such as Fibrinogen, or to counterreceptors on adjacent cells, such as the intracellular adhesion molecules (ICAMs), leading to aggregation of cells. Ligands serve to cross-link or cluster Integrins by binding to adjacent Integrin receptors; both receptor clustering and ligand occupancy are necessary for the activation of Integrinmediated responses. In addition to mediating cell adhesion and cytoskeletal organization, Integrins function as signaling receptors. Signals transduced by Integrins play a role in many ,biological processes, including cell growth, differentiation, migration and apoptosis.
Host	Rabbit
Immunogen	Synthetic peptide, corresponding to amino acids 720-770 of Human Integrin β5.
Reactivity	Human, Mouse, Rat
Recombinant	FALSE
Regulatory	RUO
Species	Homo Sapiens (Human)

Swissprot	P18084
Uniprot	P18084
Weight	100 kDa

Description	Product: 1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2. Specificity: Integrin β5 (V746) polyclonal antibody detects endogenous levels of Integrin β5 protein.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Applications

WB

Description

WB

Dilution

WB	1:500-1:1000

Datasheet

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SKU	Supplier No.	Size	Your price	Quantity
BHA11300358	BS1188	50µl	$190.44		Add to Cart
BHA11300358	BS1188	100µl	$294.44		Add to Cart

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