Coronavirus N protein is required for coronavirus RNA synthesis, and has RNA chaperone activity that may be involved in template switch. Nucleocapsid protein is a most abundant protein of coronavirus. N protein packages the positive strand viral genome RNA into a helical ribonucleocapsid (RNP) and plays a fundamental role during virion assembly through its interactions with the viral genome and membrane protein M. Plays an important role in enhancing the efficiency of subgenomic viral RNA transcription as well as viral replication. Because of the conservation of N protein sequence and its strong immunogenicity, the N protein of coronavirus is chosen as a diagnostic tool.
Tag
N-6His
Formulation
Supplied as a 0.2 uM filtered solution of PBS, pH 7.4.
Species
SARS-CoV-2
Host
E.coli
Accession Number
QHD43423.2
Accurate Molecular Mass(kd)
36.2kDa
Predicted Molecular Mass(kd)
38kDa
Protein Description
Recombinant 2019-nCoV NP (Truncated) is produced by our E.coli expression system with a 6His tag at the N-terminus.
This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs.Upon receipt, store it immediately at<-20°C.
Purity
> 95 % as determined by reducing SDS-PAGE.
Storage
Store at< -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
Immunological Activity
Immobilized Recombinant 2019-nCoV NP (Truncated)(Cat#DRA58) at 2ug/ml (100 ul/well) can bind Anti-2019-nCoV NP Antibody (6G9)(Cat#DA027), the ED50 for this effect is 4.8 ng/ml.
Reviews of Recombinant 2019-nCoV NP (Truncated) (His Tag)(Active)