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Home / Proteins & Peptide

Recombinant Human CALCB Protein (aa 1-118, Fc Tag)

SKU : BHP10302780

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Elabscience Biotechnology Co.,Ltd

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Mfr.No.	PKSH030665
Description	A DNA sequence encoding the human CALCB (P10092) (Met1-Phe118) was fused with Fc region of mouse IgG at the C-terminus.
Alternative Names	Calcitonin gene-related peptide 2; CALC2; Beta-type CGRP; Calcitonin gene-related peptide II; CALCB
Reconstitution	Please refer to the printed manual for detailed information.
Background	CALCB; also known as CGPR and calcitonin 2; belongs to the calcitonin family. CALCB is a calcitonin (CT) peptide which may play a role in the mediation of human inflammatory diseases. It is highly expressed in the skin; blood; and cerebrospinal fluid. CGRP immunolabeling (IL) was detected in epidermal keratinocytes at levels that were especially high and widespread in the skin of humans from locations afflicted with postherpetic neuralgia (PHN) and complex region pain syndrome type 1 (CRPS); of monkeys infected with simian immunodeficiency virus; and of rats subjected to L5/L6 spinal nerve ligation; sciatic nerve chronic constriction; and subcutaneous injection of complete Freund's adjuvant. Increased CGRP-IL was also detected in epidermal keratinocytes of transgenic mice with keratin-14 promoter driven overexpression of noggin; an antagonist to BMP-4 signaling. CGPR dilates a variety of vessels including the coronary; cerebral and systemic vasculature.
Reactivity	Human
Tag	C-Fc
Formulation	Lyophilized from sterile PBS; pH 7.4
Host	HEK293 Cells
Accession Number	P10092
Endotoxin Level	< 1.0 EU per ug of the protein as determined by the LAL method.
Mol Weight	36.2 kDa
Mw(kda)	36.2 kDa

Sequence Info	Met 1-Phe118

Shipping	This product is provided as lyophilized powder which is shipped with ice packs.
Stotage Note	Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Purity	> 95 % as determined by reducing SDS-PAGE.

Product Manual	Data Sheet

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SKU	Supplier No.	Size	Your price	Quantity
BHP10302780	PKSH030665	100ug	$855		Add to Cart

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