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Home / Proteins & Peptide

Recombinant Human CD300a/LMIR1 Protein (Fc Tag)

SKU : BHP10302825

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Elabscience Biotechnology Co.,Ltd

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Mfr.No.	PKSH030836
Description	A DNA sequence encoding the human CD300A (Q9UGN4-1)(Met1-Gln178) was expressed with the Fc region of human IgG1 at the C-terminus.
Alternative Names	CMRF35-Like Molecule 8; CLM-8; CD300 Antigen-Like Family Member A; CMRF-35-H9; CMRF35-H9; CMRF35-H; IRC1/IRC2; Immunoglobulin Superfamily Member 12; IgSF12; Inhibitory Receptor Protein 60; IRp60; NK Inhibitory Receptor; CD300a; CD300A; CMRF35H; IGSF12
Reconstitution	Please refer to the printed manual for detailed information.
Background	CMRF35-like molecule 8; also known as CD300 antigen-like family member A; CMRF35-H9; Immunoglobulin superfamily member 12; Inhibitory receptor protein 60; NK inhibitory receptor; CD300a and CMRF35H; is a single-pass type I membrane protein which belongs to the CD300 family. The CD300 family of myeloid immunoglobulin receptors includes activating ( CD300b; CD300e ) and inhibitory members ( CD300a; CD300f ); as well as molecules presenting a negative charge within their transmembrane domain ( CD300c; CD300d ). CD300A / IGSF12 is expressed not only by natural killer (NK) cells but also by T-cell subsets; B-cells; dendritic cells; mast cells; granulocytes and monocytes.It contains one Ig-like V-type ( immunoglobulin-like ) domain. CD300A / IGSF12 is an inhibitory receptor which may contribute to the down-regulation of cytolytic activity in natural killer (NK) cells; and to the down-regulation of mast cell degranulation. CD300c is a functional immune receptor able to deliver activating signals upon ligation in RBL-2H3 mast cells. CD300c signaling is partially mediated by a direct association with the immune receptor tyrosine-based activation motif-bearing adaptor FcepsilonRgamma. CD300a and CD300c play an important role in the cross-regulation of TNF-alpha and IFN-alpha secretion from plasmacytoid dendritic cells (pDCs).
Reactivity	Human
Tag	C-Fc
Formulation	Lyophilized from sterile PBS; pH 7.4
Host	HEK293 Cells
Accession Number	Q9UGN4-1
Endotoxin Level	< 1.0 EU per ug as determined by the LAL method.
Mol Weight	44.5 kDa
Mw(kda)	44.5 kDa

Sequence Info	Met 1-Gln178

Shipping	This product is provided as lyophilized powder which is shipped with ice packs.
Stotage Note	Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Purity	(97.9+1.1) % as determined by reducing SDS-PAGE.

Product Manual	Data Sheet

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SKU	Supplier No.	Size	Your price	Quantity
BHP10302825	PKSH030836	100ug	$732		Add to Cart

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