Please refer to the printed manual for detailed information.
Background
The cluster of differentiation (CD) system is commonly used as cell markers in immunophynotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules which associating with the immune function of the cell. There are more than 320 CD unique clusters and subclusters have been identified. Some of the CD molecules serve as receptors or ligands important to the cell through initiating a signal cascade which then alter the behavior of the cell. Some CD proteins do not take part in cell signal process but have other functions such as cell adhesion. CD7 is a transmembrane protein which is a member of the immunoglobulin superfamily. This protein is found on thymocytes and mature T cells. It plays an essential role in T-cell interactions and also in T-cell / B-cell interaction during early lymphoid development.
Reactivity
Human
Tag
C-His
Formulation
Lyophilized from sterile PBS; pH 7.4
Host
HEK293 Cells
Accession Number
NP_006128.1
Endotoxin Level
< 1.0 EU per ug as determined by the LAL method.
Bioactivity
Measured by its binding ability in a functional ELISA.Immobilized human CD7-His at 10 ug/ml (100 ul /well) can bind biotinylated SECTM1-His; The EC50 of biotinylated SECTM1-His is 11-26ng/ml.
Mol Weight
18 kDa
Mw(kda)
18 kDa
Sequence Info
Met 1-Pro 180
Shipping
This product is provided as lyophilized powder which is shipped with ice packs.
Stotage Note
Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.