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Home / Proteins & Peptide

Recombinant Human Frizzled-6/FZD6 Protein (Fc Tag)

SKU : BHP10302755

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Elabscience Biotechnology Co.,Ltd

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Mfr.No.	PKSH030518
Description	A DNA sequence encoding the human FZD6 (NP_003497.2) (Met1-Val153) was expressed with the Fc region of mouse IgG1 at the C-terminus.
Alternative Names	FZ-6;FZ6;HFZ6;NDNC10
Reconstitution	Please refer to the printed manual for detailed information.
Background	This gene represents a member of the 'frizzled' gene family, which encode 7-transmembrane domain proteins that are receptors for Wnt signaling proteins. The protein encoded by this family member contains a signal peptide, a cysteine-rich domain in the N-terminal extracellular region, and seven transmembrane domains, but unlike other family members, this protein does not contain a C-terminal PDZ domain-binding motif. This protein functions as a negative regulator of the canonical Wnt/beta-catenin signaling cascade, thereby inhibiting the processes that trigger oncogenic transformation, cell proliferation, and inhibition of apoptosis. Alternative splicing results in multiple transcript variants, some of which do not encode a protein with a predicted signal peptide.
Reactivity	Human
Tag	C-Fc
Formulation	Lyophilized from sterile PBS, pH 7.4
Host	HEK293 Cells
Accession Number	NP_003497.2
Endotoxin Level	< 1.0 EU per ug of the protein as determined by the LAL method.
Mol Weight	42 kDa
Mw(kda)	42 kDa

Sequence Info	Met 1-Val153

Shipping	This product is provided as lyophilized powder which is shipped with ice packs.
Stotage Note	Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Purity	> 90 % as determined by reducing SDS-PAGE.

Product Manual	Data Sheet

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SKU	Supplier No.	Size	Your price	Quantity
BHP10302755	PKSH030518	100ug	$855		Add to Cart

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