A DNA sequence encoding the full length of human IL17RC isoform 3 (NP_116121.2) (Met 1-Ala 454) was fused with a polyhistidine tag at the carboxy-terminus.
Alternative Names
IL17-RL;IL17RL;UNQ6118/PRO20040/PRO38901
Reconstitution
Please refer to the printed manual for detailed information.
Background
The hypomethylation within the IL17RC gene promoter in peripheral blood is not suitable for use as a clinical biomarker of AMD. This study highlights the need for considerable replication of epigenetic association studies prior to clinical application. methylation of IL17RC could play as a marker in choroidal neovascularization (CNV) and degeneration of retinal pigment epithelium (RPE) cells in vitro.
< 1.0 EU per ug of the protein as determined by the LAL method.
Bioactivity
Measured by its ability to bind with recombinant human IL17A-His in a functional ELISA.Measured by its ability to bind with recombinant human 17A in a functional ELISA.
Mol Weight
49.6 kDa
Mw(kda)
49.6 kDa
Sequence Info
Met 1-Ala 454
Shipping
This product is provided as lyophilized powder which is shipped with ice packs.
Stotage Note
Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.