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Home / Proteins & Peptide

Recombinant Human NELL2 Protein (His Tag)

SKU : BHP10302796

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Elabscience Biotechnology Co.,Ltd

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Mfr.No.	PKSH030717
Description	A DNA sequence encoding the human NELL2 (Q99435) (Met 1-Leu 816) was fused with a polyhistidine tag at the C-terminus.
Alternative Names	NRP2
Reconstitution	Please refer to the printed manual for detailed information.
Background	OX-40L, also known as TNFSF4 and CD252, is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. OX-40L is an important costimulatory molecule that plays a crucial role in the regulation of T-cell-mediated immunity. The interaction of TNFSF4-TNFSF4 is involved in the pathogenesis of multiple autoimmune and inflammatory diseases such as systemic lupus erythematosus (SLE), carotid artery disease and cancer. OX-40L is a ligand for receptor TNFRSF4/OX4. It is found to play a role in T cell antigen-presenting cell (APC) interactions. In surface Ig- and CD40-stimulated B cells, this cytokine along with CD70 has been shown to provide CD28-independent costimulatory signals to T cells. This protein and its receptor are reported to directly mediate adhesion of activated T cells to vascular endothelial cells.Immune CheckpointImmune Checkpoint Targets Co-stimulatory Immune Checkpoint Targets Immunotherapy Cancer Immunotherapy Targeted Therapy
Reactivity	Human
Tag	C-His
Formulation	Lyophilized from sterile 20mM Tris, 500mM NaCl, pH 7.4, 10% gly
Host	Baculovirus-Insect Cells
Accession Number	Q99435
Endotoxin Level	< 1.0 EU per ug of the protein as determined by the LAL method.
Mol Weight	90.4 kDa
Mw(kda)	90.4 kDa

Sequence Info	Met 1-Leu 816

Shipping	This product is provided as lyophilized powder which is shipped with ice packs.
Stotage Note	Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Purity	> 87 % as determined by reducing SDS-PAGE.

Product Manual	Data Sheet

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SKU	Supplier No.	Size	Your price	Quantity
BHP10302796	PKSH030717	50ug	$732		Add to Cart

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