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Home / Proteins & Peptide

Recombinant Human PCSK9/Proprotein Convertase 9 (biotinylated)

SKU : BHP13600017

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Beijing Solarbio Science & Technology Co., Ltd.

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Mfr.No.	P00124
Antigen	PCSK9/Proprotein Convertase 9 (biotinylated)
Background	Human Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9) is a secretory subtilase belonging to the proteinase K subfamily. PCSK9 is synthesized as a soluble zymogen that undergoes autocatalytic intramolecular processing in the ER , the pro domain and mature chain secrete together through noncovalent interactions. PCSK9 binds with low-density lipoprotein receptor (LDLR) and plays a major regulatory role in cholesterol homeostasis. Inhibition of PCSK9 function by preventing PCSK9/LDLR interaction is currently being explored as a means of lowering cholesterol levels. PCSK9 also binds to apolipoprotein receptor 2 (ApoER2), and play a role in the neural development.
Description	Recombinant Human Proprotein Convertase Subtilisin/Kexin Type 9 is produced by our Mammalian expression system and the target gene encoding Gln31-Gln152&Ser153-Gln692 is expressed with a AVI tag at the C-terminus.
Formulation	Supplied as a 0.2 μm filtered solution of 50mM HEPES,150mM NaCl,20%Glycerol,pH 7.4.
Endotoxin Level	Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test.

Synonyms	Proprotein Convertase Subtilisin/Kexin Type 9; Neural Apoptosis-Regulated Convertase 1; NARC-1; Proprotein Convertase 9; PC9; Subtilisin/Kexin-Like Protease PC9; PCSK9; NARC1

Purity	Greater than 95% as determined by reducing SDS-PAGE.
Storage	Store at < -20°C, stable for 6 months after receipt. Please minimize freeze-thaw cycles.

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SKU	Supplier No.	Size	Your price	Quantity
BHP13600017	P00124	10µg	$351.11		Add to Cart
BHP13600017	P00124	50µg	$771.11		Add to Cart

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