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Recombinant Human Phospholipid transfer protein(PLTP)

SKU : BHP10502439

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CUSABIO TECHONOLOGY LLC

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Mfr.No.	CSB-YP018212HU
Alternative Names	Lipid transfer protein II
Antigen	PLTP
Tag	N-terminal 6xHis-tagged
Regulatory	RUO
Relevance	Facilitates the transfer of a spectrum of different lipid molecules, including diacylglycerol, phosphatidic acid, sphingomyelin, phosphatidylcholine, phosphatidylglycerol, cerebroside and phosphatidyl ethanolamine. Essential for the transfer of excess surface lipids from triglyceride-rich lipoproteins to HDL, thereby facilitating the formation of smaller lipoprotein rnants, contributing to the formation of LDL, and assisting in the maturation of HDL particles. PLTP also plays a key role in the uptake of cholesterol from peripheral cells and tissues that is subsequently transported to the liver for degradation and excretion. Two distinct forms of PLTP exist in plasma: an active form that can transfer PC from phospholipid vesicles to high-density lipoproteins (HDL), and an inactive form that lacks this capability.
Source	Yeast
Notes	Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Protein Name	Recommended name: Phospholipid transfer protein; Alternative name(s): Lipid transfer protein II
Expression Region	18-493aa
Mol Weight	55.1kDa
Nature	recombinant
Protein Description	Full Length of Mature Protein

Subcellular Location	Secreted
Uniprot	P55058, P55058
Database Links	HGNC:9093 OMIM:172425 KEGG:hsa:5360 STRING:9606.ENSP00000361508 UniGene:Hs.439312
Function	Facilitates the transfer of a spectrum of different lipid molecules, including diacylglycerol, phosphatidic acid, sphingomyelin, phosphatidylcholine, phosphatidylglycerol, cerebroside and phosphatidyl ethanolamine. Essential for the transfer of excess surface lipids from triglyceride-rich lipoproteins to HDL, thereby facilitating the formation of smaller lipoprotein remnants, contributing to the formation of LDL, and assisting in the maturation of HDL particles. PLTP also plays a key role in the uptake of cholesterol from peripheral cells and tissues that is subsequently transported to the liver for degradation and excretion. Two distinct forms of PLTP exist in plasma
Pathway	PPAR signaling pathway; Cholesterol metabolism
Protein Families	BPI/LBP/Plunc superfamily, BPI/LBP family
Research Area	Transport
Tissue Specificity	Wide tissue distribution. Placenta > pancreas > lung > kidney > heart > liver > skeletal muscle > brain.
Weight	55kDa

Stotage Note	Repeated freezing and thawing is not recommended. Store working aliquots at 4℃ for up to one week.
Buffer	Tris-based buffer，50% glycerol
Purity	Greater than 90% as determined by SDS-PAGE.
Storage	The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Storage Buffer	Tris-based buffer,50% glycerol

Immunogen Species	Homo Sapiens (Human)

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SKU	Supplier No.	Size	Your price	Quantity
BHP10502439	CSB-YP018212HU	500ug	$1298		Add to Cart
BHP10502439	CSB-YP018212HU	100ug	$470		Add to Cart
BHP10502439	CSB-YP018212HU	20ug	$250		Add to Cart

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