A DNA sequence encoding the human PTRH2 (Q9Y3E5) (Gly63-Tyr179) was expressed with a polyhistidine tag at the N-terminus.
Alternative Names
BIT1;CFAP37;CGI-147;IMNEPD;PTH;PTH 2;PTH2;PTRH2
Reconstitution
Please refer to the printed manual for detailed information.
Background
PTH2, also known as PTRH2, is a mitochondrial protein which belongs to the PTH2 family. PTH 2 is released during apoptosis from the mitochondria to the cytoplasm. The natural substrate for PTH 2 may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. When in the cytoplasm, PTRH2 regulates the function of 2 transcriptional regulators, TLE5 and TLE1, thus promoting caspase-independent cell death.
Reactivity
Human
Tag
N-His
Formulation
Lyophilized from sterile 20mM Tris, 10% glycerol, pH 8.0
Host
E.coli
Accession Number
Q9Y3E5
Endotoxin Level
Please contact us for more information.
Mol Weight
14.5 kDa
Mw(kda)
14.5 kDa
Sequence Info
Gly63-Tyr179
Shipping
This product is provided as lyophilized powder which is shipped with ice packs.
Stotage Note
Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.