A DNA sequence encoding the human S100A6 (NP_055439.1) (Met 1-Gly 90) was expressed.
Alternative Names
S100A6;Protein S100-A6;Calcyclin;Growth factor-inducible protein 2A9;MLN 4;Prolactin receptor-associated protein;PRA;S100 calcium-binding protein A6;CACY;2A9;5B10;CABP;PRA
Reconstitution
Please refer to the printed manual for detailed information.
Background
S100 protein is a family of low molecular weight protein found in vertebrates characterized by two EF-hand calcium-binding motifs. There are at least 21 different S100 proteins; and the name is derived from the fact that the protein is 100% soluble in ammonium sulfate at neutral pH. Most S100 proteins are disulfide-linked homodimer; and is normally present in cells derived from the neural crest; chondrocytes; macrophages; dendritic cells; etc. S100 proteins have been implicated in a variety of intracellular and extracellular functions. They are involved in regulation of protein phosphorylation; transcription factors; the dynamics of cytoskeleton constituents; enzyme activities; cell growth and differentiation; and the inflammatory response. S100A6 (S100 calcium binding protein A6) is a member of the S100 family of proteins; and functions in prolactin secretion; and exocytosis. Chromosomal rearrangements and altered expression of S100A6 have been implicated in melanoma.
Reactivity
Human
Formulation
Lyophilized from sterile PBS; pH 7.4
Host
E.coli
Accession Number
NP_055439.1
Endotoxin Level
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Sequence Info
Met 1-Gly 90
Shipping
This product is provided as lyophilized powder which is shipped with ice packs.
Stotage Note
Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.