A DNA sequence encoding the mouse SERPINB12 (NP_082247.1) (Met 1-Pro 423) was expressed, with a C-terminal polyhistidine tag.
Alternative Names
2300003F07Rik;4833409F13Rik
Reconstitution
Please refer to the printed manual for detailed information.
Background
Serpins are the largest and most diverse family of serine protease inhibitors which are involved in a number of fundamental biological processes such as blood coagulation, complement activation, fibrinolysis, angiogenesis, inflammation and tumor suppression and are expressed in a cell-specific manner. Most serpins are secreted and attain physiologic concentrations in the blood and extracellular fluids. Mouse SerpinB12 is a cytoplasm protein which belongs to the serpin family and Ov-serpin subfamily. It is expressed in many tissues, including brain, bone marrow, lymph node, heart, lung, liver, pancreas, testis, ovary, and intestine. SerpinB12 inhibits trypsin and plasmin, but not thrombin, coagulation factor Xa, or urokinase-type plasminogen activator.
< 1.0 EU per ?g of the protein as determined by the LAL method.
Mol Weight
49.3 kDa
Mw(kda)
49.3 kDa
Sequence Info
Met 1-Pro 423
Shipping
This product is provided as lyophilized powder which is shipped with ice packs.
Stotage Note
Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.