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Home / Proteins & Peptide

Recombinant Mouse Toll-like receptor 7(Tlr7),partial

SKU : BHP10505826

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CUSABIO TECHONOLOGY LLC

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Mfr.No.	CSB-MP023606MO
Antigen	TLR7
Tag	N-terminal 10xHis-tagged and C-terminal Myc-tagged
Description	Key component of innate and adaptive immunity. TLRs (Toll-like receptors) control host immune response against pathogens through recognition of molecular patterns specific to microorganisms. TLR7 is a nucleotide-sensing TLR which is activated by single-stranded RNA. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response.
Regulatory	RUO
Relevance	Key component of innate and adaptive immunity. TLRs (Toll-like receptors) control host immune response against pathogens through recognition of molecular patterns specific to microorganisms. TLR7 is a nucleotide-sensing TLR which is activated by single-stranded RNA. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response.
Source	Mammalian cell
Notes	Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Protein Name	Recommended name: Toll-like receptor 7
Expression Region	27-348aa
Mol Weight	40.8 kDa
Nature	Recombinant
Protein Description	Partial

Subcellular Location	Endoplasmic reticulum membrane, Single-pass type I membrane protein, Endosome, Lysosome, Cytoplasmic vesicle, phagosome
Uniprot	P58681, P58681
Database Links	KEGG:mmu:170743 STRING:10090.ENSMUSP00000061853 UniGene:Mm.23979
Function	Key component of innate and adaptive immunity. TLRs (Toll-like receptors) control host immune response against pathogens through recognition of molecular patterns specific to microorganisms. TLR7 is a nucleotide-sensing TLR which is activated by single-stranded RNA. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response.
Pathway	Toll-like receptor signaling pathway
Protein Families	Toll-like receptor family
Research Area	Epigenetics and Nuclear Signaling
Weight	40.8 kDa

Stotage Note	Repeated freezing and thawing is not recommended. Store working aliquots at 4℃ for up to one week.
Buffer	Tris-based buffer，50% glycerol
Purity	Greater than 85% as determined by SDS-PAGE.
Storage	The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Storage Buffer	Tris-based buffer，50% glycerol

Immunogen Species	Mus Musculus (Mouse)

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SKU	Supplier No.	Size	Your price	Quantity
BHP10505826	CSB-MP023606MO	500ug	$5544		Add to Cart
BHP10505826	CSB-MP023606MO	100ug	$1848		Add to Cart
BHP10505826	CSB-MP023606MO	20ug	$660		Add to Cart

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