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Home / Proteins & Peptide

Recombinant Rat LAG3/CD223 Protein (His Tag)

SKU : BHP10305724

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Elabscience Biotechnology Co.,Ltd

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Mfr.No.	PKSR030201
Description	A DNA sequence encoding the rat LAG3 (Q5BK54)(Met1-Leu442) was expressed with a polyhistidine tag at the C-terminus.
Alternative Names	LAG3
Reconstitution	Please refer to the printed manual for detailed information.
Background	LAG3, also known as CD223 and Lymphocyte activation gene 3, belongs to immunoglobulin (Ig) superfamily. LAG3 contains 4 extracellular Ig-like domains. The LAG3 gene contains 8 exons. It is selectively expressed in activated T and NK cells. LAG3 has a negative regulatory function in T cells. It also acts as as a new marker of T cell induced B cell activation. As a soluble molecule, LAG3 activates antigen-presenting cells through MHC class II signalling, leading to increased antigen-specific T-cell responses in vivo.Immune CheckpointImmune Checkpoint Targets Co-inhibitory Immune Checkpoint Targets Immunotherapy Cancer Immunotherapy Targeted Therapy
Reactivity	Rat
Tag	C-His
Formulation	Lyophilized from sterile 20 mM NaAc, 500 mM NaCl, 10 % Glycerol, 0.02 % tween 20, pH 5.5
Host	HEK293 Cells
Accession Number	Q5BK54
Endotoxin Level	< 1.0 EU per ?g of the protein as determined by the LAL method
Mol Weight	47.1 kDa
Mw(kda)	47.1 kDa

Sequence Info	Met1-Leu442

Shipping	This product is provided as lyophilized powder which is shipped with ice packs.
Stotage Note	Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Purity	> 90 % as determined by SDS-PAGE

Product Manual	Data Sheet

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SKU	Supplier No.	Size	Your price	Quantity
BHP10305724	PKSR030201	100ug	$732		Add to Cart

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