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Home / Primary Antibodies / Recombinant Antibodies

Anti-ETHE1 Antibody BHA11305226

SKU : BHA11305226

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Mfr.No.	BS70132
Alternative Names	HSCO ; Sulfur dioxygenase ETHE1
Antigen	ETHE1
Categories	Primary Antibodies
Chromosome Location	19q13.31
Clonality	polyclonal
Description	ETHE1 (ethylmalonic encephalopathy 1), also known as HSCO (hepatoma subtracted clone one protein), is a 254 amino acid protein belonging to the metallo-beta-lactamase superfamily and glyoxalase II family. Localizing to the cytoplasm, nucleus and mitochondrion matrix, ETHE1 is ubiquitously expressed and may function in sulfide catabolism. ETHE1 binds two zinc ions per subunit and interacts directly with RELA, preventing its localization to the nucleus thus leading to suppressed p53-induced apoptosis. The gene encoding ETHE1 maps to human chromosome 19q13.31. Mutations to this gene result in ethylmalonic encephalopathy, an infantile metabolic disorder characterized by high levels of ethylmalonic acid, neurodevelopmental delay and regression, recurrent petechiae, acrocyanosis, and death within the first decade of life.
Host	Rabbit
Immunogen	Recombinant protein of human ETHE1.
Reactivity	Human, Mouse, Rat
Recombinant	TRUE
Regulatory	RUO
Species	Homo Sapiens (Human)

Swissprot	O95571
Uniprot	O95571
Weight	28 kDa

Description	Product: 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.3. Specificity: ETHE1 polyclonal antibody detects endogenous levels of ETHE1 protein.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Applications

WB

Description

WB

Dilution

WB	1:200-1:1000

Datasheet

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SKU	Supplier No.	Size	Your price	Quantity
BHA11305226	BS70132	50µl	$234.89		Add to Cart
BHA11305226	BS70132	100µl	$368.22		Add to Cart

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