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Home / Primary Antibodies / Recombinant Antibodies

Anti-ATP2B2 Antibody BHA11308377

SKU : BHA11308377

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Mfr.No.	BS8556
Alternative Names	Plasma membrane calcium-transporting ATPase 2 ; PMCA2 ; Plasma membrane calcium ATPase isoform 2 ; Plasma membrane calcium pump isoform 2 ; PMCA2
Antigen	ATP2B2
Categories	Primary Antibodies
Chromosome Location	3p25.3
Clonality	polyclonal
Description	Plasma membrane-type Ca2+-ATPases (PMCAs) mediate the export of bivalent calcium ions from eukaryotic cells. As members of the P class of ion-motive ATPases, PMCAs are a functionally diverse group of proteins that are derived from alternatively spliced transcripts originating from four distinct genes, PMCA1, 2, 3, and 4. The expression of different PMCA isoforms and splice variants is regulated in a developmental, tissue- and cell type-specific manner, and with respect to the physiological needs of specific cell and tissue types. Spatial and temporal rates of resting intracellular Ca2+ concentrations and Ca2+ signaling in eukaryotic cells are dependent on the array of PMCA isoforms that are expressed in concert with the rate of Ca2+ export. The human PMCA2 gene is located on chromosome 3, and antibodies directed against PMCA2 detect three proteins in brain and heart. Homozygous null mutations in the mouse gene result in deafwaddler mice, which are characterized by having a hesitant, wobbly gait, displaying head bobbing, and are deaf.
Host	Rabbit
Immunogen	Recombinant full length Human ATP2B2.
Reactivity	Human, Mouse, Rat
Recombinant	TRUE
Regulatory	RUO
Species	Homo Sapiens (Human)

Swissprot	Q01814
Uniprot	Q01814
Weight	137kDa

Description	Product: 1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol. Specificity: ATP2B2 polyclonal antibody detects endogenous levels of ATP2B2 protein.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Applications

WB

Description

WB

Dilution

WB	1:500-1:2000

Datasheet

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SKU	Supplier No.	Size	Your price	Quantity
BHA11308377	BS8556	50µl	$234.89		Add to Cart
BHA11308377	BS8556	100µl	$368.22		Add to Cart

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