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Home / Proteins & Peptide

Recombinant Human Interleukin-2 (IL2) (L100F,R101D,L105V,I106V,I112F) (Active)

BHP10506696
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Email
[email protected]
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Involvement In Disease A chromosomal aberration involving IL2 is found in a form of T-cell acute lymphoblastic leukemia (T-ALL). Translocation t(4;16)(q26;p13) with involves TNFRSF17.
Subcellular Location Secreted
Uniprot P60568
Database Links

HGNC:6001

OMIM:147680

KEGG:hsa:3558

STRING:9606.ENSP00000226730

UniGene:Hs.89679
Function Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Can stimulate B-cells, monocytes, lymphokine-activated killer cells, natural killer cells, and glioma cells.
Pathway Jak-STAT signaling pathway; PI3K-Akt signaling pathway; T cell receptor signaling pathway; Th1 and Th2 cell differentiation; Th17 cell differentiation
Protein Families IL-2 family
Research Area Immunology
Purity Greater than 95% as determined by SDS-PAGE.
Storage Buffer Lyophilized from a 0.2 μm filtered 1xPBS, pH 7.4
Immunogen Species Homo Sapiens (Human)
SKU Supplier No. Size Your price Quantity
BHP10506696 CSB-AP004711HU 10ug $96
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BHP10506696 CSB-AP004711HU 50ug $290
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BHP10506696 CSB-AP004711HU 500ug $976
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BHP10506696 CSB-AP004711HU 1mg $1392
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