Alpha-type CGRPCalcitonin gene-related peptide I ;CGRP-I
Reconstitution
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20°C/-80°C. Our default final concentration of glycerol is 50%. Customers could use it as reference.
Tag
C-terminal mFc-tagged
Molecular Weight
33.1 kDa
Relevance
CGRP induces vasodilation. It dilates a variety of vessels including the coronary, cerebral and systic vasculature. Its abundance in the CNS also points toward a neurotransmitter or neuromodulator role. It also elevates platelet cAMP.
Source
Mammalian cell
Form
Liquid or Lyophilized powder
Notes
Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Expression Region
83-119aa
Lead Time
3-7 business days
Organism
Homo sapiens (Human)
Protein Length
Partial
Uniprot
P06881
Gene Name
CALCA
Research Area
Signal Transduction
Sequence
ACDTATCVTHRLAGLLSRSGGVVKNNFVPTNVGSKAF
Buffer
If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol.<br />If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.
Purity
Greater than 95% as determined by SDS-PAGE.
Storage
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. <br />Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.