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Home / Proteins & Peptide / Recombinant Protein

Recombinant Human DNA repair protein complementing XP-G cells (ERCC5), partial

SKU : BHP10503151

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CUSABIO TECHONOLOGY LLC

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Mfr.No.	CSB-EP007773HU
Alternative Names	DNA excision repair protein ERCC-5, Xeroderma pigmentosum group G-complementing protein, DNA excision repair protein ERCC-5 ; Xeroderma pigmentosum group G-complementing protein
Tag	N-terminal 6xHis-tagged
Regulatory	RUO
Relevance	Single-stranded structure-specific DNA endonuclease involved in DNA excision repair. Makes the 3'incision in DNA nucleotide excision repair (NER). Acts as a cofactor for a DNA glycosylase that removes oxidized pyrimidines from DNA. May also be involved in transcription-coupled repair of this kind of damage, in transcription by RNA polymerase II, and perhaps in other processes too.
Source	E.coli
Notes	Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Protein Name	DNA excision repair protein ERCC-5Xeroderma pigmentosum group G-complementing protein
Expression Region	947-1186aa
Mol Weight	30.8 kDa
Nature	recombinant
Protein Description	Partial

Involvement In Disease	Xeroderma pigmentosum complementation group G (XP-G); Cerebro-oculo-facio-skeletal syndrome 3 (COFS3)
Subcellular Location	Nucleus
Uniprot	P28715, P28715
Database Links	HGNC:3437 OMIM:133530 KEGG:hsa:2073 STRING:9606.ENSP00000347978 UniGene:Hs.258429
Function	Single-stranded structure-specific DNA endonuclease involved in DNA excision repair. Makes the 3'incision in DNA nucleotide excision repair (NER). Acts as a cofactor for a DNA glycosylase that removes oxidized pyrimidines from DNA. May also be involved in transcription-coupled repair of this kind of damage, in transcription by RNA polymerase II, and perhaps in other processes too.
Pathway	DNA repair pathway
Protein Families	XPG/RAD2 endonuclease family, XPG subfamily
Weight	30.95kDa

Stotage Note	Repeated freezing and thawing is not recommended. Store working aliquots at 4℃ for up to one week.
Buffer	Tris-based buffer，50% glycerol
Purity	Greater than 90% as determined by SDS-PAGE.
Storage	The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Storage Buffer	Tris-based buffer,50% glycerol

Immunogen Species	Homo Sapiens (Human)

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SKU	Supplier No.	Size	Your price	Quantity
BHP10503151	CSB-EP007773HU	20ug	$306		Add to Cart
BHP10503151	CSB-EP007773HU	100ug	$578		Add to Cart
BHP10503151	CSB-EP007773HU	1mg	$2466		Add to Cart

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