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Home / Proteins & Peptide / Recombinant Protein

Recombinant Human Splicing factor U2AF 35KDA subunit (U2AF1)

SKU : BHP10503539

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CUSABIO TECHONOLOGY LLC

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Mfr.No.	CSB-EP025405HU
Alternative Names	U2 auxiliary factor 35 kDa subunit, U2 small nuclear RNA auxiliary factor 1, U2 snRNP auxiliary factor small subunit, U2 auxiliary factor 35 kDa subunit ; U2 small nuclear RNA auxiliary factor 1 ; U2 snRNP auxiliary factor small subunit
Tag	N-terminal GST-tagged
Regulatory	RUO
Relevance	Plays a critical role in both constitutive and enhancer-dependent splicing by mediating protein-protein interactions and protein-RNA interactions required for accurate 3'-splice site selection. Recruits U2 snRNP to the branch point. Directly mediates interactions between U2AF2 and proteins bound to the enhancers and thus may function as a bridge between U2AF2 and the enhancer complex to recruit it to the adjacent intron.
Source	E.coli
Notes	Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Expression Region	1-240aa
Mol Weight	54.9kDa
Nature	recombinant
Protein Description	Full Length

Involvement In Disease	Myelodysplastic syndrome (MDS)
Subcellular Location	Nucleus, Nucleus speckle
Uniprot	Q01081, Q01081
Database Links	HGNC:12453 OMIM:191317 KEGG:hsa:102724594 STRING:9606.ENSP00000291552 UniGene:Hs.365116
Function	Plays a critical role in both constitutive and enhancer-dependent splicing by mediating protein-protein interactions and protein-RNA interactions required for accurate 3'-splice site selection. Recruits U2 snRNP to the branch point. Directly mediates interactions between U2AF2 and proteins bound to the enhancers and thus may function as a bridge between U2AF2 and the enhancer complex to recruit it to the adjacent intron.
Protein Families	Splicing factor SR family
Research Area	Epigenetics and Nuclear Signaling
Weight	54.04kD

Stotage Note	Repeated freezing and thawing is not recommended. Store working aliquots at 4℃ for up to one week.
Buffer	Tris-based buffer，50% glycerol
Purity	Greater than 90% as determined by SDS-PAGE.
Storage	The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Storage Buffer	Tris-based buffer,50% glycerol

Immunogen Species	Homo Sapiens (Human)

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SKU	Supplier No.	Size	Your price	Quantity
BHP10503539	CSB-EP025405HU	20ug	$224		Add to Cart
BHP10503539	CSB-EP025405HU	100ug	$419		Add to Cart
BHP10503539	CSB-EP025405HU	1mg	$1812		Add to Cart

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