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Home / Proteins & Peptide / Recombinant Protein

Recombinant Marmota monax Tumor necrosis factor (TNF), partial

BHP10503478
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Email
[email protected]
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Subcellular Location Cell membrane, Single-pass type II membrane protein, SUBCELLULAR LOCATION: Tumor necrosis factor, membrane form: Membrane, Single-pass type II membrane protein, SUBCELLULAR LOCATION: Tumor necrosis factor, soluble form: Secreted, SUBCELLULAR LOCATION: C-domain 1: Secreted, SUBCELLULAR LOCATION: C-domain 2: Secreted
Uniprot O35734, O35734
Function Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation.; FUNCTION
Pathway MAPK signaling pathway; mTOR signaling pathway; TGF-beta signaling pathway; NF-kappa B signaling pathway; TNF signaling pathway; Apoptosis; Necroptosis; Antigen processing and presentation; Fc epsilon RI signaling pathway; Hematopoietic cell lineage; IL-17 signaling pathway; Natural killer cell mediated cytotoxicity; NOD-like receptor signaling pathway; Osteoclast differentiation; T cell receptor signaling pathway; Toll-like receptor signaling pathway; Adipocytokine signaling pathway; AGE-RAGE signaling pathway in diabetic complications; Inflammatory Pain
Protein Families Tumor necrosis factor family
Research Area Others
Weight 36.64kDa
Stotage Note Repeated freezing and thawing is not recommended. Store working aliquots at 4℃ for up to one week.
Buffer Tris-based buffer，50% glycerol
Purity Greater than 90% as determined by SDS-PAGE.
Storage The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Storage Buffer Tris-based buffer,50% glycerol
SKU Supplier No. Size Your price Quantity
BHP10503478 CSB-EP523593MQG 20ug $388
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