Resiquimod

Mfr.No.	AE81026SF
Description	Resiquimod (R848) is an imidazoquinoline amine and Toll-like receptor (TLR) agonist with potential immune response modifying activity. Resiquimod exerts its effect through the TLR signaling pathway by binding to and activating TLR7 and 8 mainly on dendritic cells, macrophages, and B-lymphocytes. This induces the nuclear translocation of the transcription activator NF-kB as well as activation of other transcription factors. This may lead to an increase in mRNA levels and subsequent production of cytokines, especially interferon-alpha (INF-a) and other cytokines, thereby enhancing T-helper 1 (Th1) immune responses. In addition, topical application of resiquimod appears to activate Langerhans' cells, leading to an enhanced activation of T-lymphocytes.
Alternative Names	S28463
Molecular Formula	C17H22N4O2
Signaling Pathways	Microbiology/Virology, Immunology/Inflammation, Proteases/Proteasome
Smiles	C(C(C)(C)O)N1C=2C=3C(N=C(N)C2N=C1COCC)=CC=CC3
Cas Number	144875-48-9
Molecular Weight	314.38
Target	HCV Protease, TLR

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SKU	Supplier No.	Size	Your price
BHB20436893	AE81026SF	1 mL	$43	Add to Cart
BHB20436893	AE81026SF	5 mg	$30	Add to Cart
BHB20436893	AE81026SF	10 mg	$47	Add to Cart
BHB20436893	AE81026SF	25 mg	$79	Add to Cart
BHB20436893	AE81026SF	50 mg	$139	Add to Cart
BHB20436893	AE81026SF	100 mg	$197	Add to Cart
BHB20436893	AE81026SF	200 mg	$263	Add to Cart
BHB20436893	AE81026SF	500 mg	$389	Add to Cart