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Home / Services / Virotherapeutic Solutions

Herpes Simplex Virus (HSV) Therapeutics at Brain Case

SKU : BHS17100003

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Brain Case (shenzhen) Biotech Co., Ltd

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Mfr.No.	BHS17100003
Service Type	Virotherapeutic Solutions
Service Specification	HSV
Provider	BrainCase
Provider Location	ShenZhen, PRC
Service ID/SKU	BHS17100003
Description	Herpes Simplex Virus (HSV) Therapeutics at Brain Case Pioneering Oncolytic Virotherapy with HSV Explore the forefront of cancer therapy with Brain Case's advanced Herpes Simplex Virus (HSV) solutions. Leveraging HSV's unique properties, we're transforming the landscape of oncolytic virotherapy, offering hope and innovative treatment options for various malignancies. Understanding HSV in Oncolytic Virotherapy HSV, a versatile double-stranded DNA virus, has emerged as a leading oncolytic virus in clinical settings. Its genome, rich in coding potential, allows for the encoding of numerous polypeptides, making it a robust platform for therapeutic gene delivery. The virus's ability to initiate infection through its unique UL and US sequences, coupled with its sophisticated gene expression system, makes it an ideal candidate for targeting and lysing cancer cells with precision. HSV's Mechanism of Action HSV's life cycle is intricately regulated by its alpha, beta, and gamma genes, orchestrating viral replication and host immune response elicitation. This controlled replication within tumor cells, followed by cell lysis and progeny virus release, underpins HSV's oncolytic prowess. Furthermore, the virus's selective replication in interferon-signaling-defective tumor cells ensures minimal harm to healthy tissues, enhancing its safety profile. The Advantages of Brain Case's HSV Solutions Brain Case's HSV-based therapies capitalize on the virus's wide infection spectrum, high infectivity, and rapid oncolytic timeline. Our engineered HSV platforms boast large genomic capacities for exogenous gene incorporation, providing a versatile tool for multi-gene-related disease treatment. Coupled with the availability of antiviral controls like acyclovir, our HSV therapies ensure safety and efficacy. Enhancing HSV for Oncolytic Efficacy At Brain Case, we're continually refining our HSV vectors to maximize their therapeutic potential while mitigating concerns such as neurotoxicity and immune clearance. Through genetic modifications like ICP34.5 deletion and incorporation of immune-modulatory genes, our HSV variants like T-VEC and G47Δ have demonstrated significant clinical success in treating melanoma and glioma, respectively. Brain Case's HSV Product Lineup Our diverse range of HSV-based products is designed to meet the varied needs of oncology research and therapy: BC-HSV-Hs01: HSV-EYFP, offering fluorescent tracking capabilities. BC-HSV-Hs05: HSV-mCherry, for red fluorescent anterograde tracing. BC-HSV-Hs10: HSV-WT, the foundational wild-type strain for basic research. BC-HSV-Hs15: HSV-ΔG-EYFP, a customizable pseudovirus platform. BC-HSV-Hs20: HSV-ΔG, adaptable for adding functional components. Future Directions and Clinical Integration With ongoing advancements in genetic engineering and combinational therapies, Brain Case's HSV platforms are set to revolutionize oncolytic virotherapy. Our commitment to enhancing tumor specificity, reducing potential side effects, and integrating with existing cancer treatments paves the way for more effective and personalized therapeutic strategies. Join Brain Case in the Oncolytic Revolution Embrace the transformative power of HSV with Brain Case's cutting-edge virotherapy solutions. For more information or to collaborate on your next project, contact us and step into the future of cancer therapy.
Keywords/Tags	Herpes Simplex Virus, Oncolytic Virotherapy, Cancer Therapy, HSV Engineering, Clinical Applications, Gene Delivery
Geographic Availability	Global

Payment Terms	Net 30
Additional Costs	shipping
Currency Accepted	USD
Refund Policy	non refundable

Certifications	RUO
Quality Control Steps	QC report, Validation
Safety Protocols	Biosafety Level
Support Availability	8/5, Business Hours
Customer Reviews or Ratings	4.5-star
Support Channels	Email, Chat
FAQ Section	Yes
Response Time	Within 24 hours
Handling Capabilities	Biohazard Level 2, Biohazard Level 1, Cold Chain, Sterile
Packaging Options	Plastic tubes
Customization Options	Protocol modification

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