JavaScript is currently not supported/disabled by this browser. Please enable JavaScript for full functionality.

Call Us 1 - 866 - 986 - 9598
[email protected]

Sign Up

Login
- My Order
- Return Requests
- Track my Order

Home / Biochemicals / Small Molecules

(-)-Nicotine ditartrate

SKU : BHB21300232

An Agonist of nAChR

Contact us to order

Tel

+1 866.986.9598

Email

[email protected]

Get a Quote

Request More Infos

Alomone Labs

view supplier details

Order Now

Credit card payments now incur a 3% fee.

Contact us to order

Tel

+1 866.986.9598

Email

[email protected]

Get a Quote

Ask Merchant

Request More Infos

Sample Request

Mfr.No.	N-175, N-175_1 g, N-175_10 g, N-175_25 g, N-175_5 g
Description	(-)-Nicotine ditartrate (#N-175) is a highly pure, synthetic, and biologically active compound.
Molecular Formula	C18H26N2O12.
Background	The nAChR complex, a cholinergic receptor, is composed of five subunits and is found in both the peripheral and central nervous systems. In the mammalian brain, there are as many as nine alpha subunits (alpha2 to alpha10) and three beta subunits (beta2 to beta4). The most abundant receptor subtypes in the brains of humans are alpha4/beta2, alpha3/beta4, and alpha71.(-)-Nicotine ditartrate is a potent agonist of AChR. It stimulates autonomic ganglia and skeletal muscle neuromuscular junctions2. (-)-Nicotine ditartrate is a salt of nicotine of pharmaceutical grade and tartaric acid used for preparation of the products for smoking cessation and as an analytical standard3.
Shipping	Shipped at room temperature. Product as supplied can be stored intact at room temperature for several weeks. For longer periods, it should be stored at -20°C
Concentration	0.5-200 uM.
Reconstitution	Water. Centrifuge all product preparations before use (10000 x g 5 min).
Cas Number	65-31-6
Molecular Weight	462.4
Solubility	Water. Centrifuge all product preparations before use (10000 x g 5 min).
Target	nAChR
Source	Synthetic
Activity	(-)-Nicotine ditartrate activates alpha7 nAChR with EC50 ~25 uM1.
Country Of Origin	Israel/IL
UNSPSC Code	41116134
Application	FC- Flow cytometry, IFC- Indirect flow cytometry, IHC- Immunohistochemistry,LCI- Live cell imaging, Calcium imaging assay,Cell survival assay, Electrophysiology, Neurite outgrowth assay
Lead Time	1-2 Business Days
Notes	Bioassay Tested: Yes Chemical Name: (S)-(-)-1-Methyl-2-(3-pyridyl)pyrrolidine (+)-ditartrate salt.

Purity	>99%
Form	Lyophilized powder.
Storage	Storage After Reconstitution: The reconstituted solution can be stored at 4°C for up to 1 week. For longer periods (up to 6 months), small aliquots should be stored at -20°C. We do not recommend storing the product in working solutions for longer than a few days. Avoid multiple freeze-thaw cycles. Storage of solutions: Up to four weeks at 4°C or three months at -20°C.

Product Manual	SDS

Reference	Xiao, Y. et al. (1998) Mol. Pharmacol. 54, 322. Rand M.J. et al. (1989) Prog. Brain Res. 79, 3. Athawale R.B. et al. (2010) Asian J. Chem. 22, 2501. Amar, M. et al. (1993) FEBS Lett. 327, 284.

Have you used this product?

Rate it now..!!

Login to Review

Combination SKU	Supplier No.	Size	Your price	Quantity
BHB21300232-1	N-175_1 g	1 g	$91		Add to Cart
BHB21300232-2	N-175_10 g	10 g	$167		Add to Cart
BHB21300232-3	N-175_25 g	25 g	$223		Add to Cart
BHB21300232-4	N-175_5 g	5 g	$129		Add to Cart

ebiohippo.com provides biomedical researchers with a one-stop informatic shopping experience by transforming biotechnology products’ data into a ready-to-analyze state. We collect and unify suppliers’ data on a single platform to reduce the time of searching, uncertainty, and cost of scientific experiments.

© 2025 Biohippo. All rights reserved.