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Home / Biochemicals / Small Molecules

(S)-AMPA

SKU : BHB21300015

An Agonist of AMPA Receptors

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Alomone Labs

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Mfr.No.	A-267, A-267_1 mg, A-267_10 mg, A-267_25 mg, A-267_5 mg, A-267_50 mg
Description	(S)-AMPA (#A-267) is a highly pure, synthetic, and biologically active compound.
Molecular Formula	C7H10N2O4.
Synonyms	Synthetic
Background	(S)-AMPA enantiomer is a synthetic AMPA receptor agonist. The compound mimics the effects of the glutamate neurotransmitter1.Ionotropic glutamate AMPA receptors (AMPARs) are the primary receptors that mediate fast excitatory synaptic transmission in the mammalian brain. The majority of this transmission in the mammalian central nervous system is mediated by the release of glutamate from the presynaptic terminal and its binding to glutamate receptors on the postsynaptic membrane2.
Shipping	Shipped at room temperature. Product as supplied can be stored intact at room temperature for several weeks. For longer periods, it should be stored at -20°C
Concentration	0.01-10 uM.
Reconstitution	100 mM in H2O. Centrifuge all products before reconstitution (10000 x g 5 min).
Cas Number	83643-88-3
Molecular Weight	186.17
Solubility	100 mM in H2O. Centrifuge all products before reconstitution (10000 x g 5 min).
Target	AMPA receptors
Activity	An active enantiomer of AMPA (EC50 = 3.5 uM)1.
Country Of Origin	Israel/IL
UNSPSC Code	41116134
Application	FC- Flow cytometry, IFC- Indirect flow cytometry, IHC- Immunohistochemistry,LCI- Live cell imaging, Calcium imaging assay,Cell survival assay, Electrophysiology, Neurite outgrowth assay
Lead Time	1-2 Business Days
Notes	Bioassay Tested: Yes Chemical Name: (2S)-2-amino-3-(5-methyl-3-oxo-1,2-oxazol-4-yl)propanoic acid.

Purity	>99% (HPLC)
Form	Lyophilized powder.
Storage	Storage After Reconstitution: The reconstituted solution can be stored at 4°C for up to 1 week. For longer periods (up to 6 months), small aliquots should be stored at -20°C. We do not recommend storing the product in working solutions for longer than a few days. Avoid multiple freeze-thaw cycles. Storage of solutions: Up to four weeks at 4°C or three months at -20°C. It is recommended to aliquot reconstituted stock solutions.

Product Manual	SDS

Reference	Falch, E. et al. (1998) J. Med. Chem. 41, 2513. Guntupalli, S. et al. (2016) Neural. Plast. 2016, 3204519. Falch, E. et al. (1998) J. Med. Chem. 41, 2513.

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Combination SKU	Supplier No.	Size	Your price	Quantity
BHB21300015-1	A-267_1 mg	1 mg	$66		Add to Cart
BHB21300015-2	A-267_10 mg	10 mg	$202		Add to Cart
BHB21300015-3	A-267_25 mg	25 mg	$451		Add to Cart
BHB21300015-4	A-267_5 mg	5 mg	$117		Add to Cart
BHB21300015-5	A-267_50 mg	50 mg	$808		Add to Cart

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