JavaScript is currently not supported/disabled by this browser. Please enable JavaScript for full functionality.

Call Us 1 - 866 - 986 - 9598
[email protected]

Sign Up

Login
- My Order
- Return Requests
- Track my Order

Home / Biochemicals / Small Molecules

Azasetron

SKU : BHB21300010

A Potent and Selective Antagonist of 5-HT3 Channels

Contact us to order

Tel

+1 866.986.9598

Email

[email protected]

Get a Quote

Request More Infos

Alomone Labs

view supplier details

Order Now

Credit card payments now incur a 3% fee.

Contact us to order

Tel

+1 866.986.9598

Email

[email protected]

Get a Quote

Ask Merchant

Request More Infos

Sample Request

Mfr.No.	A-240, A-240_10 mg, A-240_25 mg, A-240_5 mg, A-240_50 mg
Description	Azasetron (#A-240) is a highly pure, synthetic, and biologically active compound.
Molecular Formula	C17H20ClN3O3.
Synonyms	Synthetic
Background	Azasetron is a potent and selective 5-HT3 receptor antagonist. It antagonizes the channel by binding to 5-HT3 receptors thereby blocking the serotonin binding site and antagonizing the indirect sympathomimetic responses to 5-HT3.The compound is classified as a derivative of benzamide with a longer duration of action and higher affinity than other 5-HT3 receptor antagonists.Azasetron is highly effective in preventing postoperative and chemotherapy-induced nausea and vomiting induced by anticancer drugs and radiotherapy1,2. Therefore, in most cases 5-HT3 receptor antagonists are co-administered with anticancer drugs3.The 5-HT3 receptor subtype is a member of the cys-loop ligand-gated cation channels expressed throughout the central and peripheral nervous systems and mediate a variety of important physiological functions4.
Shipping	Shipped at room temperature. Product as supplied can be stored intact at room temperature for several weeks. For longer periods, it should be stored at -20°C
Concentration	0.1-100 nM.
Reconstitution	100-150 mM in DMSO. Centrifuge all product preparations before use (10000 x g 5 min).
Cas Number	123040-93-7
Molecular Weight	349.8
Solubility	100-150 mM in DMSO. Centrifuge all product preparations before use (10000 x g 5 min).
Target	5-HT3A, 5-HT3B
Activity	Azasetron is a potent and selective 5-HT3 channel blocker with Ki ~2.9 nM1.
Country Of Origin	Israel/IL
UNSPSC Code	41116134
Application	FC- Flow cytometry, IFC- Indirect flow cytometry, IHC- Immunohistochemistry,LCI- Live cell imaging, Calcium imaging assay,Cell survival assay, Electrophysiology, Neurite outgrowth assay
Lead Time	1-2 Business Days
Notes	Bioassay Tested: Yes Chemical Name: N-(1-azabicyclo(2.2.2)octan-3-yl)-6-chloro-4-methyl-3-oxo-1,4-benzoxazine-8-carboxamide.

Purity	>98%
Form	Lyophilized powder.
Storage	Storage After Reconstitution: The reconstituted solution can be stored at 4°C for up to 1 week. For longer periods (up to 6 months), small aliquots should be stored at -20°C. We do not recommend storing the product in working solutions for longer than a few days. Avoid multiple freeze-thaw cycles. Storage of solutions: Up to four weeks at 4°C or three months at -20°C.

Product Manual	SDS

Reference	Yun, M.J. et al. (2010) Yonsei. Med. J. 51, 88. Lee, H.Y. et al. (2014) Cancer Res. Treat. 46, 19. Niwa, T. et al. (2006) Biol. Pharm. Bull. 29, 1931. Kato, S. et al. (2013) Biol. Pharm. Bull. 36, 1406. Fukuda, T. et al. (1991) Eur. J. Pharmacol. 196, 299.

Have you used this product?

Rate it now..!!

Login to Review

Combination SKU	Supplier No.	Size	Your price	Quantity
BHB21300010-1	A-240_10 mg	10 mg	$254		Add to Cart
BHB21300010-2	A-240_25 mg	25 mg	$569		Add to Cart
BHB21300010-3	A-240_5 mg	5 mg	$151		Add to Cart
BHB21300010-4	A-240_50 mg	50 mg	$1019		Add to Cart

ebiohippo.com provides biomedical researchers with a one-stop informatic shopping experience by transforming biotechnology products’ data into a ready-to-analyze state. We collect and unify suppliers’ data on a single platform to reduce the time of searching, uncertainty, and cost of scientific experiments.

© 2025 Biohippo. All rights reserved.