JavaScript is currently not supported/disabled by this browser. Please enable JavaScript for full functionality.

Call Us 1 - 866 - 986 - 9598
[email protected]

Sign Up

Login
- My Order
- Return Requests
- Track my Order

Home / Biochemicals / Small Molecules

Calyculin A

SKU : BHB21300069

A Potent Inhibitor of Protein Phosphatase 1 and Protein Phosphatase 2

Contact us to order

Tel

+1 866.986.9598

Email

[email protected]

Get a Quote

Request More Infos

Alomone Labs

view supplier details

Order Now

Credit card payments now incur a 3% fee.

Contact us to order

Tel

+1 866.986.9598

Email

[email protected]

Get a Quote

Ask Merchant

Request More Infos

Sample Request

Mfr.No.	C-100, C-100_0.1 mg, C-100_10 mcg, C-100_25 mcg, C-100_50 mcg
Description	Calyculin A (#C-100) is a highly pure, natural, and biologically active compound.
Molecular Formula	C50H81N4O15P.
Background	Calyculin A was initially isolated from the marine sponge Discodermia calyx.1 It is a very potent, cell-permeable PP-1 and PP-2 inhibitor (IC50 2nM and 0.5-1nM respectively),2 and extremely specific for PP-1 and PP-2A among other acidic, alkaline and protein phosphatases.2,3
Shipping	Shipped at room temperature. Product as supplied can be stored intact at room temperature for several weeks. For longer periods, it should be stored at -20°C
Concentration	10-100 nM.
Reconstitution	DMSO, ethanol, acetone, or methanol. Centrifuge all product preparations before use (10000 x g 5 min).
Cas Number	101932-71-2
Molecular Weight	1009.2
Solubility	DMSO, ethanol, acetone, or methanol. Centrifuge all product preparations before use (10000 x g 5 min).
Source	Natural
Activity	Calyculin A is a very potent, cell-permeable PP-1 and PP-2 inhibitor (IC50 = 2 nM and 0.5-1 nM respectively)1.
Country Of Origin	Israel/IL
UNSPSC Code	41116134
Application	FC- Flow cytometry, IFC- Indirect flow cytometry, IHC- Immunohistochemistry,LCI- Live cell imaging, Calcium imaging assay,Cell survival assay, Electrophysiology, Neurite outgrowth assay
Lead Time	1-2 Business Days
Notes	Bioassay Tested: Yes Chemical Name: N-((3S)-(4-(1E)-3-((2R,3R,4R,7S,8S,9R)-2-((1S,3S,4S,5R, 7E,9E,11E,13Z)-14-Cyano-3,5-dihydroxy-1-methoxy-4,6,8,9 ,13-pentamethyl-7,9,11,13-tetradecatetraenyl)-9-hydroxy -4,4,8-trimethyl-3-(phosphonooxy)-1,6-dioxaspiro(4.5)de c-7-yl)-1-propenyl)-2-oxazoly)butyl)-4-deoxy-4-(dimethy lamino)-5-O-methyl-L-ribonamide.

Purity	>98% (HPLC)
Form	Lyophilized Powder
Storage	Storage After Reconstitution: The reconstituted solution can be stored at 4°C for up to 1 week. For longer periods (up to 6 months), small aliquots should be stored at -20°C. We do not recommend storing the product in working solutions for longer than a few days. Avoid multiple freeze-thaw cycles. Storage before Reconstitution: The product is shipped as a lyophilized powder at room temperature. Upon receipt, store the product at -20°C. Protect from moisture. Storage of solutions: Up to one week at 4°C or three months at -20°C.Protect from light.

Product Manual	SDS

Reference	Bechem, M. and Hoffman, H. (1993) Pflugers Arch. 424, 343. Hecheler, J. et al. (1988) Pflugers Arch. 412, 248. Kateo, Y. et. al. (1996) J. Am. Chem. Soc. 108, 8712178. Bechem, M. and Hoffman, H. (1993) Pflugers Arch. 424, 343.

Have you used this product?

Rate it now..!!

Login to Review

Combination SKU	Supplier No.	Size	Your price	Quantity
BHB21300069-1	C-100_0.1 mg	0.1 mg	$856		Add to Cart
BHB21300069-2	C-100_10 mcg	10 mcg	$167		Add to Cart
BHB21300069-3	C-100_25 mcg	25 mcg	$334		Add to Cart
BHB21300069-4	C-100_50 mcg	50 mcg	$535		Add to Cart
BHB21300069-5	C-100_10 mcg	5x10 mcg	$669		Add to Cart

ebiohippo.com provides biomedical researchers with a one-stop informatic shopping experience by transforming biotechnology products’ data into a ready-to-analyze state. We collect and unify suppliers’ data on a single platform to reduce the time of searching, uncertainty, and cost of scientific experiments.

© 2025 Biohippo. All rights reserved.