JavaScript is currently not supported/disabled by this browser. Please enable JavaScript for full functionality.

Call Us 1 - 866 - 986 - 9598
[email protected]

Sign Up

Login
- My Order
- Return Requests
- Track my Order

Home / Biochemicals / Small Molecules

N-Me-aminopyrimidinone 9

SKU : BHB21300245

A Specific Blocker of NaV1.7 Channel

Contact us to order

Tel

+1 866.986.9598

Email

[email protected]

Get a Quote

Request More Infos

Alomone Labs

view supplier details

Order Now

Credit card payments now incur a 3% fee.

Contact us to order

Tel

+1 866.986.9598

Email

[email protected]

Get a Quote

Ask Merchant

Request More Infos

Sample Request

Mfr.No.	N-310, N-310_10 mg, N-310_25 mg, N-310_5 mg, N-310_50 mg
Description	N-Me-aminopyrimidinone 9 (#N-310) is a highly pure, synthetic, and biologically active compound.
Molecular Formula	C16H21N3OS.
Background	N-Me-aminopyrimidinone 9, is a synthetic blocker of NaV1.7 channel. It has an effective concentration of 10 nM - 1 uM and an IC50 of 100 nM for NaV1.7 channel in its inactive state.NaV channels contribute to physiological and pathophysiological electrical signaling in nerve and muscle cells. NaV1.7 is highly expressed on the exons somatic afferent neurons and is thought to play an important role in the signaling of inflammatory pain.
Shipping	Shipped at room temperature. Product as supplied can be stored intact at room temperature for several weeks. For longer periods, it should be stored at -20°C
Concentration	10 nM - 1 uM.
Reconstitution	Centrifuge the vial before adding solvent (10,000 x g for 5 minutes) to spin down all the powder to the bottom of the vial. The lyophilized product may be difficult to visualize. Add solvent directly to the centrifuged vial. Tap the vial to aid in dissolving the lyophilized product. Tilt and gently roll the liquid over the walls of the vial. Avoid vigorous vortexing. Light vortexing for up to 3 seconds is acceptable if needed. The product is soluble in pure water at high micromolar concentrations (100 uM - 1 mM). For long-term storage in solution, we recommend preparing a stock solution by dissolving the product in double-distilled water (ddH2O) at a concentration between 100-1000x of the final working concentration. Divide the stock solution into small aliquots and store at -20°C. Before use, thaw the relevant vial(s) and dilute to the desired working concentration in your working buffer. Centrifuge all product preparations before use. It is recommended to prepare fresh solutions in working buffers just before use. Avoid multiple freeze-thaw cycles to maintain biological activity.
Cas Number	1356834-62-2
Molecular Weight	303.4
Solubility	50 mM in DMSO. Centrifuge all product preparations before use (10000 x g 5 min).
Target	NaV1.7 channels
Source	Synthetic
Activity	N-Me-aminopyrimidinone 9 is a NaV1.7 channel blocker with IC50 value of 100 nM for NaV1.7 channels in their inactivated state1.
Country Of Origin	Israel/IL
UNSPSC Code	41116134
Application	FC- Flow cytometry, IFC- Indirect flow cytometry, IHC- Immunohistochemistry,LCI- Live cell imaging, Calcium imaging assay,Cell survival assay, Electrophysiology, Neurite outgrowth assay
Lead Time	1-2 Business Days
Notes	Bioassay Tested: Yes Chemical Name: 6-amino-2-((4-tert-butylphenyl)methylsulfanyl)-3-methylpyrimidin-4-one.

Purity	>98%
Form	Lyophilized powder.
Storage	Storage After Reconstitution: The reconstituted solution can be stored at 4°C for up to 1 week. For longer periods (up to 6 months), small aliquots should be stored at -20°C. We do not recommend storing the product in working solutions for longer than a few days. Avoid multiple freeze-thaw cycles. Storage of solutions: Up to four weeks at 4°C or three months at -20°C.

Product Manual	SDS

Reference	Nguyen, H.N. et al. (2012) Bioorg. Med. Chem. Lett. 22, 1055. Nguyen, H.N. et al. (2012) Bioorg. Med. Chem. Lett. 22, 1055.

Have you used this product?

Rate it now..!!

Login to Review

Combination SKU	Supplier No.	Size	Your price	Quantity
BHB21300245-1	N-310_10 mg	10 mg	$184		Add to Cart
BHB21300245-2	N-310_25 mg	25 mg	$366		Add to Cart
BHB21300245-3	N-310_5 mg	5 mg	$117		Add to Cart
BHB21300245-4	N-310_50 mg	50 mg	$595		Add to Cart

ebiohippo.com provides biomedical researchers with a one-stop informatic shopping experience by transforming biotechnology products’ data into a ready-to-analyze state. We collect and unify suppliers’ data on a single platform to reduce the time of searching, uncertainty, and cost of scientific experiments.

© 2025 Biohippo. All rights reserved.