JavaScript is currently not supported/disabled by this browser. Please enable JavaScript for full functionality.

Call Us 1 - 866 - 986 - 9598
[email protected]

Sign Up

Login
- My Order
- Return Requests
- Track my Order

Home / Biochemicals / Small Molecules

Ricasetron

SKU : BHB21300304

A Potent Antagonist of 5-HT3 Receptors

Contact us to order

Tel

+1 866.986.9598

Email

[email protected]

Get a Quote

Request More Infos

Alomone Labs

view supplier details

Order Now

Credit card payments now incur a 3% fee.

Contact us to order

Tel

+1 866.986.9598

Email

[email protected]

Get a Quote

Ask Merchant

Request More Infos

Sample Request

Mfr.No.	R-150, R-150_10 mg, R-150_25 mg, R-150_5 mg, R-150_50 mg
Description	Ricasetron (#R-150) is a highly pure, synthetic, and biologically active compound.
Molecular Formula	C19H27N3O.
Synonyms	Synthetic
Background	Ricasetron, also named BRL 46470A, is a highly potent and selective blocker of 5-HT3 channels. The compound shows no obvious affinity for other 5-HT receptor subtypes.In human, ricasetron demonstrates good absorption and tolerance with wide therapeutic range1.in vivo studies of several animal models of anxiety, Ricasetron showed a significant reduction in passive and provoked interaction responses following acute and chronic administration. These findings suggest that Ricasetron may have potent psychopharmacological properties that can contribute to treating anxiety1,2.Studies show that Ricasetron is 100 times more potent than ondansetron, and 1000 times more potent than the standard anxiolytic diazepam in rat models. In these experiments the compound showed long duration of action1,2.The 5-HT3 receptor mediates the action of serotonin in the body. This receptor is a member of the Cys-loop ligand-gated cation channels, which are expressed throughout the central and peripheral nervous systems and mediates a variety of physiological functions such as emotion, cognition, memory, pain perception, and gastrointestinal functions including secretion and motility3.
Shipping	Shipped at room temperature. Product as supplied can be stored intact at room temperature for several weeks. For longer periods, it should be stored at -20°C
Concentration	0.1 nM - 1 uM.
Reconstitution	Centrifuge the vial before adding solvent (10,000 x g for 5 minutes) to spin down all the powder to the bottom of the vial. The lyophilized product may be difficult to visualize. Add solvent directly to the centrifuged vial. Tap the vial to aid in dissolving the lyophilized product. Tilt and gently roll the liquid over the walls of the vial. Avoid vigorous vortexing. Light vortexing for up to 3 seconds is acceptable if needed. The product is soluble in pure water at high micromolar concentrations (100 uM - 1 mM). For long-term storage in solution, we recommend preparing a stock solution by dissolving the product in double-distilled water (ddH2O) at a concentration between 100-1000x of the final working concentration. Divide the stock solution into small aliquots and store at -20°C. Before use, thaw the relevant vial(s) and dilute to the desired working concentration in your working buffer. Centrifuge all product preparations before use. It is recommended to prepare fresh solutions in working buffers just before use. Avoid multiple freeze-thaw cycles to maintain biological activity
Cas Number	117086-68-7
Molecular Weight	313.22
Solubility	150 mM in DMSO. Centrifuge all product preparations before use (10000 x g 5 min).
Target	5-HT3 receptors
Activity	Ricasetron is a 5-HT3 antagonist with Ki 0.32 nM1.
Country Of Origin	Israel/IL
UNSPSC Code	41116134
Application	FC- Flow cytometry, IFC- Indirect flow cytometry, IHC- Immunohistochemistry,LCI- Live cell imaging, Calcium imaging assay,Cell survival assay, Electrophysiology, Neurite outgrowth assay
Lead Time	1-2 Business Days
Notes	Bioassay Tested: Yes Chemical Name: 3,3-dimethyl-N-((1R,5S)-8-methyl-8-azabicyclo(3.2.1)octan-3-yl)-2H-indole-1-carboxamide.

Purity	>99%
Form	Lyophilized powder.
Storage	Storage After Reconstitution: The reconstituted solution can be stored at 4°C for up to 1 week. For longer periods (up to 6 months), small aliquots should be stored at -20°C. We do not recommend storing the product in working solutions for longer than a few days. Avoid multiple freeze-thaw cycles. Storage of solutions: Up to four weeks at 4°C or three months at -20°C.

Product Manual	SDS

Reference	Link, C.G. et al. (1993) Br. J. Clin. Pharmacol. 35, 395. Blackburn, T.P. et al. (1993) Psychopharmacology (Berl). 110, 257. Kato, S. (2013) Biol. Pharm. Bull. 36, 1406. Blackburn, T.P. et al. (1993) Psychopharmacology (Berl). 110, 257.

Have you used this product?

Rate it now..!!

Login to Review

Combination SKU	Supplier No.	Size	Your price	Quantity
BHB21300304-1	R-150_10 mg	10 mg	$202		Add to Cart
BHB21300304-2	R-150_25 mg	25 mg	$451		Add to Cart
BHB21300304-3	R-150_5 mg	5 mg	$117		Add to Cart
BHB21300304-4	R-150_50 mg	50 mg	$808		Add to Cart

ebiohippo.com provides biomedical researchers with a one-stop informatic shopping experience by transforming biotechnology products’ data into a ready-to-analyze state. We collect and unify suppliers’ data on a single platform to reduce the time of searching, uncertainty, and cost of scientific experiments.

© 2025 Biohippo. All rights reserved.