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Home / Biochemicals / Small Molecules

Tetrodotoxin citrate free

SKU : BHB21300353

A Classic Blocker of a Subset of NaV Channels

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Alomone Labs

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Mfr.No.	T-500, T-500_1 mg
Description	Tetrodotoxin citrate free (#T-500) is a highly pure, natural, and biologically active compound.
Molecular Formula	C11H17N3O8.
Synonyms	Natural
Background	Tetrodotoxin (TTX) is an established potent and selective blocker of some NaV channels.1 Moreover, TTX sensitivity is used to define subclasses of NaV channels.2 It is widely used both to probe NaV activity and to reduce or block excitability in neurophysiological preparations.
Shipping	Shipped at room temperature. Product as supplied can be stored intact at room temperature for several weeks. For longer periods, it should be stored at -20°C
Concentration	100 nM - 1 uM.
Reconstitution	Acidic buffer (pH 4.8). Centrifuge all product preparations before use (10000 x g 5 min).
Cas Number	4368-28-9
Molecular Weight	319.28
Solubility	Acidic buffer (pH 4.8). Centrifuge all product preparations before use (10000 x g 5 min).
Target	Various NaV Na+ channels
Activity	Tetrodotoxin is a potent and selective blocker of a subclass of NaV channels1, and is often used to define subclasses of NaV channels2.
Country Of Origin	Israel/IL
UNSPSC Code	41116134
Application	FC- Flow cytometry, IFC- Indirect flow cytometry, IHC- Immunohistochemistry,LCI- Live cell imaging, Calcium imaging assay,Cell survival assay, Electrophysiology, Neurite outgrowth assay
Lead Time	1-2 Business Days
Notes	Bioassay Tested: Yes Chemical Name: Octahydro-12-(hydroxymethyl)-2-imino-5,9:7,10adimethano-10aH-(1,3)dioxocino(6,5-d)pyrimidine-4,7,10,11,12-pentol.

Purity	>99% (HPLC)
Form	Lyophilized Powder
Storage	Storage of solutions: Up to one week at 4°C or six months at -20°C.

Product Manual	SDS

Reference	Narahashi, T. et al. (1964) J. Gen. Physiol. 47, 965. Hille, B. (2001) In: Ion Channels in Excitable Membranes (third edition) chapter 3. Narahashi, T. et al. (1964) J. Gen. Physiol. 47, 965. Hille, B. (2001) In: Ion Channels in Excitable Membranes (third edition) chapter 3.

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Combination SKU	Supplier No.	Size	Your price	Quantity
BHB21300353-1	T-500_1 mg	1 mg	$615		Add to Cart
BHB21300353-2	T-500_1 mg	5x1 mg	$2460		Add to Cart

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