Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Reactivity
Human, Rat
uniprot enrty name
SRBP1_HUMAN
Note
This product is for research use only.
Clonality
polyclonal
Buffer
PBS, pH 7.4, 150 mM NaCl, 0.02% sodium azide and 50% glycerol.
Recommended Dilution
Optimal dilutions/concentrations should be determined by the end user.
Description
Phospho-SREBP-1 (Ser439) Antibody detects endogenous levels of SREBP-1 only when phosphorylated at Serine 439. This gene encodes a transcription factor that binds to the sterol regulatory element-1 (SRE1), which is a decamer flanking the low density lipoprotein receptor gene and some genes involved in sterol biosynthesis. The protein is synthesized as a precursor that is attached to the nuclear membrane and endoplasmic reticulum.