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Home / Primary Antibodies

SREBP1 Antibody (V8099)

SKU : BHA17117531

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NSJ Bioreagents

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Mfr.No.	V8099, V8099-20UG, V8099-100UG
Antigen	SREBP1
Clonality	Monoclonal
Description	The low density lipoprotein (LDL) receptor mediates the endocytic uptake of cholesterol-carrying lipoproteins, thereby controlling cholesterol levels in cells and plasma. Transcription of the LDL receptor gene is controlled by a ten base pair sequence in the 5' flanking region, designated sterol regulatory element 1 (SRE-1). When cellular sterol stores are depleted, the element is activated, the gene is transcribed and the cellular uptake of LDL increases. A set of SREbinding proteins (SREBPs) have been identified, including two basic helixloop-helix-leucine zipper (bHLH-zip) transcription factors, designated SREBP-1 and SREBP-2. SREBP-1 and SREBP-2 have been shown to have the same specificity for SRE-1 in vitro and to activate the transcription of reporter genes containing SRE-1 in the same way.
Formulation	0.2 mg/ml with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
Host	Mouse
Immunogen Region	A recombinant full-length human protein was used as the immunogen for this SREBP1 antibody.
Isotype	IgG2b,kappa
Predicted Reactivity	Human
Reactivity	Human
Recombinant	No

Uniprot	P36956
Clone No	SREBP1/1578

Concentration	0.2 mg/ml
Format	Purified
Purification	Protein G affinity chromatography
Storage	Store the SREBP1 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).

Applications	ELISA
Dilution	ELISA (order BSA-free format for coating)

Product Manual	Data Sheet

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Combination SKU	Supplier No.	Size	Your price	Quantity
BHA17117531-1	V8099-20UG	20ug	$219		Add to Cart
BHA17117531-2	V8099-100UG	100ug	$499		Add to Cart

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