{"product_id":"17-dmag-bhb11900005","title":"17-DMAG","description":"\u003cp\u003e17-DMAG (17-dimethylaminoethylamino-17-demethoxygeldanamycin) is a water-soluble, bioavailable analog of geldanamycin and 17-AAG, designed to overcome the solubility and toxicity limitations of its predecessors. As a high-affinity HSP90 inhibitor, 17-DMAG disrupts the stability of client proteins involved in neurodegenerative disease pathways. Preclinical studies highlight its ability to induce autophagy and promote the clearance of alpha-synuclein aggregates, a hallmark of Parkinson’s disease and related disorders. Its favorable pharmacokinetic profile, including efficient tissue distribution and reduced metabolic degradation, makes 17-DMAG a compelling candidate for CNS-targeted therapies. By enhancing proteostasis and mitigating protein aggregation, 17-DMAG represents a promising tool for modulating neurodegenerative processes at the molecular chaperone level.\u003c\/p\u003e","brand":"StressMarq Biosciences Inc.","offers":[{"title":"1 mg","offer_id":53040943366509,"sku":"SIH-114A","price":125.0,"currency_code":"USD","in_stock":true},{"title":"5 mg","offer_id":53040963846509,"sku":"SIH-114-5MG","price":412.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/SIH-114_17-DMAG_Chemical_Structure.png?v=1771837624","url":"https:\/\/www.ebiohippo.com\/products\/17-dmag-bhb11900005","provider":"BioHippo","version":"1.0","type":"link"}