{"product_id":"2-3-dinor-8-iso-prostaglandin-f2-alpha-bhb20445863","title":"2,3-dinor-8-iso Prostaglandin F2α","description":"\u003cstyle\u003e\n.bhp-desc{font-size:16px;color:#1a1a1a;line-height:1.7}\n.bhp-desc h2{font-size:18px;font-weight:700;color:#003366;margin:24px 0 10px;padding-bottom:6px;border-bottom:2px solid #003366}\n.bhp-desc p{margin:0 0 12px}\n.bhp-desc .bhp-spec-table{width:100%;border-collapse:collapse;margin:12px 0 18px}\n.bhp-desc .bhp-spec-table th{width:36%;text-align:left;padding:8px 12px;background:#e8f0fb;color:#003366;font-weight:600;vertical-align:top;border:1px solid #ccd9f0}\n.bhp-desc .bhp-spec-table td{padding:8px 12px;vertical-align:top;border:1px solid #ccd9f0}\n.bhp-desc .bhp-warning-box{background:#fff8e6;border-left:4px solid #e6a817;padding:10px 14px;margin:10px 0 14px;border-radius:0 4px 4px 0}\n\u003c\/style\u003e\n\u003cdiv class=\"bhp-desc\"\u003e\n  \u003ch2\u003eCompound Overview\u003c\/h2\u003e\n  \u003cp\u003e\u003cstrong\u003e2,3-dinor-8-iso Prostaglandin F2α\u003c\/strong\u003e (CAS 221664-05-7) is a research-grade small molecule supplied by TargetMol.\u003c\/p\u003e\n\n  \u003ch2\u003ePhysical Properties\u003c\/h2\u003e\n  \u003ctable class=\"bhp-spec-table\"\u003e\n    \u003ctr\u003e\n\u003cth\u003eCAS Number\u003c\/th\u003e\n\u003ctd\u003e221664-05-7\u003c\/td\u003e\n\u003c\/tr\u003e\n    \u003ctr\u003e\n\u003cth\u003eForm\u003c\/th\u003e\n\u003ctd\u003eSolid\u003c\/td\u003e\n\u003c\/tr\u003e\n    \u003ctr\u003e\n\u003cth\u003eShipping\u003c\/th\u003e\n\u003ctd\u003eRoom Temperature (RT)\u003c\/td\u003e\n\u003c\/tr\u003e\n  \u003c\/table\u003e\n  \u003ch2\u003eBiological Activity\u003c\/h2\u003e\n  \u003cp\u003e8-isoProstaglandin F2alpha (8-isoPGF2alpha; 8-isoprostane) is a byproduct of non-specific lipid peroxidation, resembling prostaglandin in structure. In humans and rats, its metabolite, 12,3-dinor-8-isoPGF2alpha, is formed following exogenous administration of 8-isoPGF2alpha, which is converted to 2,3-dinor-8-isoPGF1alpha and 2,3-dinor-8-isoPGF2alpha. Additionally, rat hepatocytes can further break down 8-isoPGF2alpha into a beta-oxidation product, 2,3,4,5-tetranor-8-isoPGF2alpha. The metabolite, 2,3-dinor-8-isoPGF2alpha, is normally found in human urine at concentrations of 200-300 pg\/ml. Its levels rise in conditions associated with oxidative stress, such as smoking, demonstrating a correlation with the concentration of its precursor, 8-isoPGF2alpha.\u003c\/p\u003e\n  \u003ch2\u003eSafety \u0026amp; Regulatory\u003c\/h2\u003e\n  \u003cdiv class=\"bhp-warning-box\"\u003e\n    \u003cp\u003e\u003cstrong\u003eFor Research Use Only (RUO).\u003c\/strong\u003e Not for therapeutic, diagnostic, or clinical use. Wear appropriate PPE and consult the Safety Data Sheet (SDS) prior to handling.\u003c\/p\u003e\n  \u003c\/div\u003e\n\u003c\/div\u003e","brand":"TargetMol","offers":[{"title":"25 ug","offer_id":53327295480173,"sku":"T84593-25UG","price":189.0,"currency_code":"USD","in_stock":true},{"title":"50 ug","offer_id":53327432286573,"sku":"T84593-50UG","price":352.0,"currency_code":"USD","in_stock":true},{"title":"100 ug","offer_id":53327432319341,"sku":"T84593-100UG","price":658.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/CgoaEGZ9RlOEYP1TAAAAAFjTkKI277.png?v=1778722324","url":"https:\/\/www.ebiohippo.com\/products\/2-3-dinor-8-iso-prostaglandin-f2-alpha-bhb20445863","provider":"BioHippo","version":"1.0","type":"link"}