{"product_id":"adipoq-antibody-adiponectin-bha17135638","title":"Adipoq Antibody \/ Adiponectin","description":"\u003ch2\u003eOverview\u003c\/h2\u003e\u003cp\u003eAdipoq Antibody \/ Adiponectin is a anti-Adipoq Rabbit antibody Recombinant Rabbit Monoclonal clone 30A64 supplied in Liquid format. Recommended for workflows such as Western blot (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF) with listed reactivity in Mouse.\u003c\/p\u003e\u003ch2\u003eKey elements and design rationale\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eTarget:\u003c\/strong\u003e Adipoq\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eAntibody details:\u003c\/strong\u003e Rabbit, Recombinant Rabbit Monoclonal, clone 30A64, isotype Rabbit IgG\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eFormat:\u003c\/strong\u003e Liquid\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eApplications (as listed):\u003c\/strong\u003e WB, IHC, ICC, IF\u003c\/li\u003e\n\u003c\/ul\u003e\u003ch2\u003eBiological background\u003c\/h2\u003e\u003cdiv\u003eAdipoq antibody detects adiponectin, a hormone encoded by the ADIPOQ gene. Adiponectin is also known as adipocyte complement related protein of 30 kDa and Acrp30. It is secreted by adipocytes and circulates in serum in multiple oligomeric forms, including trimeric, hexameric, and high molecular weight complexes. Adiponectin binds receptors ADIPOR1 and ADIPOR2, activating AMPK and PPAR signaling pathways to regulate glucose metabolism, lipid catabolism, and insulin sensitivity.\u003cbr\u003e\u003cbr\u003eAdipoq antibody is widely applied in endocrinology, metabolism research, and cardiovascular biology. Adiponectin improves insulin sensitivity and has anti inflammatory and anti atherogenic properties. Reduced adiponectin levels are associated with obesity, type 2 diabetes, metabolic syndrome, and coronary artery disease. By detecting adiponectin, researchers can evaluate how adipose tissue hormones regulate systemic metabolism and disease risk.\u003cbr\u003e\u003cbr\u003e ELISA quantifies circulating adiponectin in serum and plasma, while western blotting detects its oligomeric forms. Immunohistochemistry maps adiponectin expression in adipose tissue and other metabolic organs. These applications provide powerful tools for exploring adipokine biology.\u003cbr\u003e\u003cbr\u003eAdiponectin has protective roles in vascular biology, reducing endothelial activation and inhibiting smooth muscle proliferation. It also influences inflammation by modulating cytokine production and macrophage polarization. Dysregulation of adiponectin contributes to insulin resistance, atherosclerosis, and nonalcoholic fatty liver disease. By applying Adipoq antibody, scientists can study mechanisms linking adipose tissue function to systemic metabolism and cardiovascular health.\u003cbr\u003e\u003cbr\u003eAdipoq antibody from\u003c\/div\u003e\u003ch2\u003eResearch relevance and current trends\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003eConnecting protein-level changes to phenotype using orthogonal readouts (genetic perturbation, transcriptomics, imaging).\u003c\/li\u003e\n\u003cli\u003eConsidering isoforms and post-translational regulation when interpreting protein-level changes.\u003c\/li\u003e\n\u003cli\u003eComparing results across species and model systems with matched controls.\u003c\/li\u003e\n\u003c\/ul\u003e\u003ch2\u003eCommon research applications\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eWestern blotting:\u003c\/strong\u003e compare relative abundance and activation-state changes across conditions.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eImmunofluorescence:\u003c\/strong\u003e visualize subcellular distribution and cell-to-cell heterogeneity.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eImmunohistochemistry:\u003c\/strong\u003e map target signal in tissue context and compare regions\/phenotypes.\u003c\/li\u003e\n\u003c\/ul\u003e\u003cp\u003eInterpret changes in signal alongside appropriate controls and, when relevant, in parallel with total-protein or pathway readouts.\u003c\/p\u003e\u003ch2\u003eNotes for experimental interpretation\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003eSignal can reflect expression level, isoform composition, and post-translational state; interpret results in the context of your model system and stimuli.\u003c\/li\u003e\n\u003cli\u003eSpecies differences and sample matrices can influence epitope recognition; prioritize matched controls and orthogonal confirmation when feasible.\u003c\/li\u003e\n\u003c\/ul\u003e\u003cp\u003e\u003cstrong\u003eAntibody notes:\u003c\/strong\u003e Monoclonal antibodies provide a defined epitope recognition profile that can support consistent comparisons across experiments.\u003c\/p\u003e\u003c!-- Sources (internal): - UniProt search — UniProt — https:\/\/www.uniprot.org\/uniprotkb?query=Adipoq - NCBI Gene search — NCBI — https:\/\/www.ncbi.nlm.nih.gov\/gene\/?term=Adipoq - Ensembl search — Ensembl — https:\/\/www.ensembl.org\/Multi\/Search\/Results?q=Adipoq - Human Protein Atlas search — HPA — https:\/\/www.proteinatlas.org\/search\/Adipoq - PubMed (review) — NLM — https:\/\/pubmed.ncbi.nlm.nih.gov\/?term=Adipoq+review --\u003e","brand":"NSJ Bioreagents","offers":[{"title":"Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg\/ml BSA \/ 100 ul","offer_id":53047299047789,"sku":"FY12735","price":449.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/get_image_da3e85eb-bfd2-4b34-9b52-657a0ab82159.jpg?v=1772019336","url":"https:\/\/www.ebiohippo.com\/products\/adipoq-antibody-adiponectin-bha17135638","provider":"BioHippo","version":"1.0","type":"link"}