{"product_id":"aged-mouse-aortic-smooth-muscle-cells-bhc16400845","title":"Aged Mouse Aortic Smooth Muscle Cells","description":"\u003ch2\u003eOverview\u003c\/h2\u003e\u003cp\u003eAged Mouse Aortic Smooth Muscle Cells are primary age-defined smooth muscle cells derived from mouse aortic tissue. Product metadata indicate adherent growth with smooth muscle-like morphology and a reported BSL-2 handling context. Depending on the selected variant, the product may be supplied in selectable cryopreserved and flask formats (Frozen Vial (0.5 x 10^6 cells), T25 Flask, and T75 Flask) for in vitro studies that benefit from tissue-relevant cellular context.\u003c\/p\u003e\u003ch2\u003eKey elements and design rationale\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003eSource and identity reflect the stated smooth muscle cells model and tissue origin, supporting experiments where aortic\/musculoskeletal context matters.\u003c\/li\u003e\n\u003cli\u003eReported classifications and phenotype descriptors include primary, aged, adherent growth, smooth muscle-like morphology, and age metadata: Aged.\u003c\/li\u003e\n\u003cli\u003eSelectable variants can include Frozen Vial (0.5 x 10^6 cells), T25 Flask, and T75 Flask; choose the listed format according to culture scale, handling preference, and downstream assay design.\u003c\/li\u003e\n\u003cli\u003eHandling considerations should follow institutional practice appropriate for the reported BSL-2 classification and the datasheet associated with the selected format.\u003c\/li\u003e\n\u003c\/ul\u003e\u003cp\u003eReview the specification table and variant selector together when choosing the appropriate format for assay scale, tissue context, and downstream readouts.\u003c\/p\u003e\u003ch2\u003eBiological background\u003c\/h2\u003e\u003cp\u003eSmooth muscle cells regulate contractility, tone, and structural remodeling in vascular and visceral tissues. Their phenotype can shift between contractile and synthetic states depending on culture context, passage history, and experimental stimulation. In this case, the stated aortic tissue and musculoskeletal context can influence morphology, baseline signaling, and assay responsiveness.\u003c\/p\u003e\u003ch2\u003eResearch relevance and current trends\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003eTissue-specific cell-state differences remain important when selecting in vitro models for mechanistic and comparative studies.\u003c\/li\u003e\n\u003cli\u003eMultiparametric readouts such as cell culture, imaging, and immunofluorescence are commonly combined to connect morphology, phenotype, and pathway-level response.\u003c\/li\u003e\n\u003cli\u003eComparisons across donor source, passage, tissue origin, or model state can help separate model-specific effects from assay-specific effects.\u003c\/li\u003e\n\u003c\/ul\u003e\u003ch2\u003eCommon research applications\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003eCell culture and condition-optimization studies to assess morphology, growth behavior, or baseline phenotype over time.\u003c\/li\u003e\n\u003cli\u003eImaging-based workflows to track morphology, localization, marker expression, cell-cell interactions, or reporter-linked signal.\u003c\/li\u003e\n\u003c\/ul\u003e\u003cp\u003eChanges in morphology, marker expression, proliferation, migration, barrier properties, reporter activity, or secreted factors are typically interpreted alongside matched controls and the selected culture conditions.\u003c\/p\u003e\u003ch2\u003eNotes for experimental interpretation\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003ePotential confounders include donor-to-donor variability, passage-dependent phenotypic drift, substrate effects, serum or media composition, and differences between cryopreserved and expansion-stage material.\u003c\/li\u003e\n\u003cli\u003eUse matched controls and confirm identity with morphology- and marker-based readouts suited to the stated cell type, tissue source, and downstream assay.\u003c\/li\u003e\n\u003cli\u003eAge-defined cell sources can be informative for experiments that compare age-associated changes in signaling, barrier function, matrix biology, or stress responses.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp style=\"display:none\"\u003eSKU:BHC16400845\u003c\/p\u003e","brand":"Cell Biologics Inc","offers":[{"title":"Frozen Vial (0.5 x 10^6 cells)","offer_id":53195807490413,"sku":"A57-6080-FV-0.5M","price":580.0,"currency_code":"USD","in_stock":true},{"title":"T25 Flask","offer_id":53196097880429,"sku":"A57-6080-T25","price":630.0,"currency_code":"USD","in_stock":true},{"title":"T75 Flask","offer_id":53196097913197,"sku":"A57-6080-T75","price":890.0,"currency_code":"USD","in_stock":true}],"url":"https:\/\/www.ebiohippo.com\/products\/aged-mouse-aortic-smooth-muscle-cells-bhc16400845","provider":"BioHippo","version":"1.0","type":"link"}