{"product_id":"anhydroryanodine-bhb21300046","title":"Anhydroryanodine","description":"\u003ch3\u003eProduct details\u003c\/h3\u003e \u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eChemical name:\u003c\/strong\u003e 1H-Pyrrole-2-carboxylic acid, 3a,4,5,6,7,7a,8,8aoctahydro-3a,4,7a,8a-tetrahydroxy-3,5,8-trimethyl-2-(1-methylethyl)-10-oxo-1H-3b,8-(epoxy ethano)cyclopent(a)inden-1-yl ester, (1R-(1-alpha,3a-beta,3b-alpha,4-alpha,5-beta,7a-beta,8-alpha,8a-beta))-.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eCAS number:\u003c\/strong\u003e 6883-31-4\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eMolecular formula:\u003c\/strong\u003e C25H33NO8.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePurity:\u003c\/strong\u003e \u0026gt;98%\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eConcentration:\u003c\/strong\u003e 100 µM - 1 mM.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eForm:\u003c\/strong\u003e Lyophilized Powder\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSolubility:\u003c\/strong\u003e Methanol. Centrifuge all product preparations before use (10000 x g 5 min).\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eReconstitution:\u003c\/strong\u003e Methanol. Centrifuge all product preparations before use (10000 x g 5 min).\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eShipping:\u003c\/strong\u003e Shipped at room temperature. Product as supplied can be stored intact at room temperature for several weeks. For longer periods, it should be stored at -20°C.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSource:\u003c\/strong\u003e Natural\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eActivity:\u003c\/strong\u003e Anhydroryanodine is a non-active analogue of ryanodine1.\u003c\/li\u003e\n\u003c\/ul\u003e \u003ch3\u003eScientific background\u003c\/h3\u003e \u003cp\u003eRyanodine (#R-500) is a natural alkaloid isolated from the stem and roots of Ryania Speciosa, a shrub that grows in tropical locations in Central and South America. Ryanodine is a modulator of intracellular Ca2+ release channels1.Ryanodine was found to be a potent paralysis inducer of skeletal and cardiac muscles2 by inhibiting the SR Ca2+ release through direct binding with the high affinity Ryanodine receptor (RyR) Ca2+ channel as a tetrameric complex2,3.Anhydroryanodine is an anhydrous non-active form of ryanodine obtained by dehydration of ryanodine4. Anhydroryanodine can be used as a negative control for ryanodine activity4.\u003c\/p\u003e \u003cp\u003e\u003cstrong\u003eLead time:\u003c\/strong\u003e 1-2 Business Days\u003c\/p\u003e \u003cp\u003e\u003cstrong\u003eCountry of origin:\u003c\/strong\u003e Israel\/IL\u003c\/p\u003e \u003ch3\u003eApplications key\u003c\/h3\u003e \u003cp\u003eApplication key: FC- Flow cytometry, IFC- Indirect flow cytometry, IHC- Immunohistochemistry,LCI- Live cell imaging, Calcium imaging assay,Cell survival assay, Electrophysiology, Neurite outgrowth assay.\u003c\/p\u003e","brand":"Alomone Labs","offers":[{"title":"50 mcg \/ 1","offer_id":53249705050477,"sku":"A-510-50MCG-1","price":354.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/A-510_str-1.gif?v=1778544414","url":"https:\/\/www.ebiohippo.com\/products\/anhydroryanodine-bhb21300046","provider":"BioHippo","version":"1.0","type":"link"}