{"product_id":"anti-aldh7a1-polyclonal-antibody-bha21402008","title":"Anti-ALDH7A1 Polyclonal Antibody","description":"\u003cp\u003e\u003cstrong\u003eOverview\u003c\/strong\u003e\u003cbr\u003e\nAnti-ALDH7A1 Polyclonal Antibody targets \u003cstrong\u003eALDH7A1\u003c\/strong\u003e (Aldehyde dehydrogenase family 7 member A1). Commonly used in ELISA, IHC, WB workflows. Research contexts include Molecular \u0026amp; Cellular Biology.\u003c\/p\u003e\n\n\u003cp\u003e\u003cstrong\u003eAlso known as:\u003c\/strong\u003e Aldehyde dehydrogenase family 7 member A1, ALDH7A1, Delta1-piperideine-6-carboxylate dehydrogenase, Antiquitin-1, P6c dehydrogenase, Alpha-AASA dehydrogenase, Alpha-aminoadipic semialdehyde dehydrogenase, Betaine aldehyde dehydrogenase, ATQ1.\u003c\/p\u003e\n\n\u003ch3\u003eTarget biology\u003c\/h3\u003e\n\u003cp\u003eALDH7A1 (aldehyde dehydrogenase 7A1; also called antiquitin) is a metabolic enzyme involved in lysine degradation and detoxification of reactive aldehydes. Disruption of ALDH7A1 function is associated with pyridoxine-dependent epilepsy due to accumulation of lysine-pathway intermediates. ALDH7A1 is therefore a useful marker in metabolism and cellular stress-response studies. Common names in the literature include: Aldehyde dehydrogenase family 7 member A1, ALDH7A1, Delta1-piperideine-6-carboxylate dehydrogenase, Antiquitin-1, P6c dehydrogenase, Alpha-AASA dehydrogenase. Typical localization reported for this class of target is cytosol and\/or mitochondria (metabolic compartments).\u003c\/p\u003e\n\n\u003ch3\u003eHow this antibody helps\u003c\/h3\u003e\n\u003cp\u003eAs a polyclonal reagent, this antibody can provide enhanced sensitivity through multi-epitope recognition. Use it to profile target expression and localization and to compare signal across conditions with matched controls.\u003c\/p\u003e\n\n\u003ch3\u003eAntigen \/ immunogen context\u003c\/h3\u003e\u003cp\u003eE. coli - derived recombinant Human ALDH7A1 (Met1-Gln539).\u003c\/p\u003e\n\n\u003ch3\u003eRecommended experimental notes\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003eTitrate the antibody to optimize signal-to-noise for your specific sample type and detection system.\u003c\/li\u003e\n\u003cli\u003eUse appropriate positive and negative controls (e.g., target-high vs target-low samples, KO\/KD where available).\u003c\/li\u003e\n\u003cli\u003eFor Western blotting, include fresh protease inhibitors and confirm the dominant band at the expected molecular weight; additional bands may reflect isoforms or processing.\u003c\/li\u003e\n\u003cli\u003eFor IHC, optimize fixation and antigen retrieval (buffer\/pH\/heat) and include isotype\/secondary-only controls to assess background.\u003c\/li\u003e\n\u003cli\u003eFor ELISA, optimize coating\/capture conditions and validate dynamic range with appropriate standards or reference samples.\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003ch3\u003eAdditional notes\u003c\/h3\u003e\u003cp\u003eFor research use only.\u003c\/p\u003e\n\n\u003cp\u003e\u003cem\u003eFor research use only. Not for diagnostic procedures.\u003c\/em\u003e\u003c\/p\u003e","brand":"Biohippo Inc","offers":[{"title":"50 ug","offer_id":53036810797421,"sku":"HW546014-50UG","price":100.0,"currency_code":"USD","in_stock":true},{"title":"100 ug","offer_id":53037394002285,"sku":"HW546014-100UG","price":160.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/HW546014-WB-1.jpg?v=1771743828","url":"https:\/\/www.ebiohippo.com\/products\/anti-aldh7a1-polyclonal-antibody-bha21402008","provider":"BioHippo","version":"1.0","type":"link"}