{"product_id":"anti-bcma-antibody-bha18200022","title":"Anti-BCMA Antibody","description":"\u003cstyle\u003e\n.bhp-desc{font-size:16px;color:#1a1a1a;line-height:1.7}\n.bhp-desc h2{font-size:18px;font-weight:700;color:#003366;margin:24px 0 10px;padding-bottom:6px;border-bottom:2px solid #003366}\n.bhp-desc p{margin:0 0 12px}\n.bhp-desc .bhp-spec-table{width:100%;border-collapse:collapse;margin:12px 0 18px}\n.bhp-desc .bhp-spec-table th{width:36%;text-align:left;padding:8px 12px;background:#e8f0fb;color:#003366;font-weight:600;vertical-align:top;border:1px solid #ccd9f0}\n.bhp-desc .bhp-spec-table td{padding:8px 12px;vertical-align:top;border:1px solid #ccd9f0}\n.bhp-desc .bhp-qc-badge{display:inline-block;background:#e6f4ea;color:#1a7a3c;border:1px solid #a8d5b5;border-radius:4px;padding:6px 14px;font-size:14px;font-weight:600}\n.bhp-desc .bhp-warning-box{background:#fff8e6;border-left:4px solid #e6a817;padding:10px 14px;margin:10px 0 14px;border-radius:0 4px 4px 0}\n.bhp-desc .bhp-cat-pill{display:inline-block;background:#003366;color:#fff;border-radius:20px;padding:3px 12px;font-size:13px;margin-bottom:10px}\n\u003c\/style\u003e\u003cdiv class=\"bhp-desc\"\u003e\n\u003cp class=\"bhp-cat-pill\"\u003eImmunotherapy, CAR-T\u003c\/p\u003e\n\u003ch2\u003eProduct Overview\u003c\/h2\u003e\n\u003cp\u003eThis anti-BCMA antibody is a purified, biotinylated, recombinant human monoclonal antibody which recognizes the human BCMA protein. BCMA is also known as tumor necrosis factor receptor superfamily member 17 (TNFRSF17) and is expressed on the surface of plasma cells. BCMA is important for plasma cell differentiation and B cell proliferation. BCMA is a validated therapeutic target in multiple myeloma. The first anti-BCMA CAR-T cell therapy (idecabt agene vicleucel) was approved by the FDA in 2021.\u003c\/p\u003e\n\u003ctable class=\"bhp-spec-table\"\u003e\n\u003ctr\u003e\n\u003cth\u003eClonality\u003c\/th\u003e\n\u003ctd\u003eMonoclonal\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth\u003eHost\u003c\/th\u003e\n\u003ctd\u003eHuman\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth\u003eAntibody Type\u003c\/th\u003e\n\u003ctd\u003eIgG1\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth\u003eIsotype\u003c\/th\u003e\n\u003ctd\u003eIgG1\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth\u003eReactivity\u003c\/th\u003e\n\u003ctd\u003eHuman\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth\u003ePurification\u003c\/th\u003e\n\u003ctd\u003eProtein A affinity chromatography (HEK293)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth\u003ePurity\u003c\/th\u003e\n\u003ctd\u003e≥90%\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth\u003eMolecular Weight\u003c\/th\u003e\n\u003ctd\u003e~146 kDa (Anti-BCMA HC: 50 kDa; Anti-BCMA LC: 23 kDa)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth\u003eFormulation\u003c\/th\u003e\n\u003ctd\u003e8 mM phosphate, pH 7.4, 110 mM NaCl, 2.2 mM KCl, 20% glycerol\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth\u003eUniProt\u003c\/th\u003e\n\u003ctd\u003eQ02223\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth\u003eStorage\u003c\/th\u003e\n\u003ctd\u003eAt least 12 months at -80°C.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/table\u003e\n\u003ch2\u003eValidated Applications\u003c\/h2\u003e\n\u003cul\u003e\u003cli\u003eWestern Blot\u003c\/li\u003e\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eAssay conditions:\u003c\/strong\u003e See datasheet for detailed information\u003c\/p\u003e\n\u003ch2\u003eImmunogen \/ Antigen Information\u003c\/h2\u003e\n\u003cp\u003eImmunogen information not provided. Please refer to the product datasheet for detailed antigen information.\u003c\/p\u003e\n\u003ch2\u003eCross-Reactivity \u0026amp; Specificity\u003c\/h2\u003e\n\u003cp\u003eThis antibody recognizes human BCMA. It has not been tested with other species.\u003c\/p\u003e\n\u003ch2\u003eSafety \u0026amp; Handling\u003c\/h2\u003e\n\u003cdiv class=\"bhp-warning-box\"\u003e\n\u003cstrong\u003eBiosafety Level:\u003c\/strong\u003e Not applicable (BSL-1)\u003c\/div\u003e\n\u003cp\u003eAvoid freeze\/thaw cycles.\u003c\/p\u003e\n\u003cp\u003eFor Research Use Only (RUO). Not for diagnostic, therapeutic, or clinical use. Handle with standard laboratory precautions (gloves, safety glasses, lab coat). Avoid freeze-thaw cycles. Consult SDS prior to use.\u003c\/p\u003e\n\u003ch2\u003eRelated Products\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e79465\u003c\/li\u003e\n\u003cli\u003e100173\u003c\/li\u003e\n\u003cli\u003e100689\u003c\/li\u003e\n\u003cli\u003e100761\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e","brand":"BPS Bioscience","offers":[{"title":"100 ug","offer_id":53327923446125,"sku":"101219","price":295.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/101219_gel_1.png?v=1778728310","url":"https:\/\/www.ebiohippo.com\/products\/anti-bcma-antibody-bha18200022","provider":"BioHippo","version":"1.0","type":"link"}