{"product_id":"anti-cdh3-msln-bite-antibody-amg-305-bha21404982","title":"Anti-CDH3\/MSLN BiTE Antibody (AMG 305)","description":"\u003cp\u003e\u003cstrong\u003eOverview\u003c\/strong\u003e\u003cbr\u003eAntibody against CDH3\/MSLN BiTE (Pre-pro-megakaryocyte-potentiating factor) for research detection of protein expression and localization.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eTarget biology\u003c\/strong\u003e\u003cbr\u003eCDH3 encodes a cell-adhesion molecule that mediates cell–cell or cell–matrix interactions and can regulate migration, immune-cell trafficking and signaling. Adhesion molecules are frequently profiled in inflammation, endothelial biology and cancer metastasis research.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eExpected localization\u003c\/strong\u003e\u003cbr\u003ePlasma membrane (often enriched at cell–cell junctions); may be shed or internalized depending on regulation.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eResearch context\u003c\/strong\u003e\u003cbr\u003eThis target is frequently studied in the context of \u003cem\u003eECM \u0026amp; Cell Adhesion\u003c\/em\u003e research. Application suitability (e.g., ELISA, FCM) is indicated in the specifications; conditions should be optimized by titration. Species reactivity information is provided in the specifications (reported: Human).\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eRecommended experimental notes\u003c\/strong\u003e\u003c\/p\u003e\u003cul\u003e\u003cli\u003eFor ELISA, ensure capture\/detection antibody compatibility and run a standard curve; verify sample matrix effects with spike-and-recovery and dilution linearity.\u003c\/li\u003e\u003c\/ul\u003e\u003cp\u003e\u003cstrong\u003eControls \u0026amp; interpretation\u003c\/strong\u003e\u003cbr\u003eWhere possible, confirm specificity using genetic perturbation (KO\/KD\/CRISPR), peptide competition (if applicable), or an orthogonal readout. Include a negative control sample expected to express low\/none of CDH3\/MSLN BiTE, and a positive control sample known to express CDH3\/MSLN BiTE.\u003c\/p\u003e\u003cp\u003e\u003cem\u003eFor research use only. Not for diagnostic procedures.\u003c\/em\u003e\u003c\/p\u003e","brand":"Biohippo Inc","offers":[{"title":"50 ug","offer_id":53036912836973,"sku":"HB245023-50UG","price":191.0,"currency_code":"USD","in_stock":true},{"title":"100 ug","offer_id":53037497614701,"sku":"HB245023-100UG","price":370.0,"currency_code":"USD","in_stock":true},{"title":"1 mg","offer_id":53037497647469,"sku":"HB245023-1MG","price":1858.0,"currency_code":"USD","in_stock":true}],"url":"https:\/\/www.ebiohippo.com\/products\/anti-cdh3-msln-bite-antibody-amg-305-bha21404982","provider":"BioHippo","version":"1.0","type":"link"}