{"product_id":"anti-denv-2-nsp5-ns5-antibody-4a1-bha21405648","title":"Anti-DENV-2 NSP5\/NS5 Antibody (4A1)","description":"\u003cp\u003e\u003cstrong\u003eOverview\u003c\/strong\u003e\u003cbr\u003eAntibody against DENV-2 NSP5\/NS5 (RNA-directed RNA polymerase NS5) for research detection of protein expression and localization.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eTarget biology\u003c\/strong\u003e\u003cbr\u003eRNA-directed RNA polymerase NS5 is a polymerase involved in nucleic-acid synthesis, contributing to DNA replication\/repair or RNA transcription depending on the polymerase class. Polymerase expression and recruitment are key readouts in genome integrity and transcriptional regulation studies.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eExpected localization\u003c\/strong\u003e\u003cbr\u003ePrimarily nuclear for host polymerases; viral polymerases may localize to virus-specific replication compartments.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eResearch context\u003c\/strong\u003e\u003cbr\u003eThis target is frequently studied in the context of \u003cem\u003eMolecular \u0026amp; Cellular Biology\u003c\/em\u003e research. Application suitability (e.g., ELISA) is indicated in the specifications; conditions should be optimized by titration. Species reactivity information is provided in the specifications (reported: Dengue virus type 2 (strain 16681-PDK53) (DENV-2)).\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eRecommended experimental notes\u003c\/strong\u003e\u003c\/p\u003e\u003cul\u003e\u003cli\u003eFor ELISA, ensure capture\/detection antibody compatibility and run a standard curve; verify sample matrix effects with spike-and-recovery and dilution linearity.\u003c\/li\u003e\u003c\/ul\u003e\u003cp\u003e\u003cstrong\u003eControls \u0026amp; interpretation\u003c\/strong\u003e\u003cbr\u003eWhere possible, confirm specificity using genetic perturbation (KO\/KD\/CRISPR), peptide competition (if applicable), or an orthogonal readout. Include a negative control sample expected to express low\/none of DENV-2 NSP5\/NS5, and a positive control sample known to express DENV-2 NSP5\/NS5.\u003c\/p\u003e\u003cp\u003e\u003cem\u003eFor research use only. Not for diagnostic procedures.\u003c\/em\u003e\u003c\/p\u003e","brand":"Biohippo Inc","offers":[{"title":"50 ug","offer_id":53036935086445,"sku":"VK651023-50UG","price":191.0,"currency_code":"USD","in_stock":true},{"title":"100 ug","offer_id":53037541392749,"sku":"VK651023-100UG","price":370.0,"currency_code":"USD","in_stock":true},{"title":"1 mg","offer_id":53037541425517,"sku":"VK651023-1MG","price":1858.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/VK651023-SDS-PAGE-1.jpg?v=1771746031","url":"https:\/\/www.ebiohippo.com\/products\/anti-denv-2-nsp5-ns5-antibody-4a1-bha21405648","provider":"BioHippo","version":"1.0","type":"link"}