{"product_id":"anti-gapdh-rabbit-polyclonal-antibody-bha13715006","title":"Anti-GAPDH Rabbit Polyclonal Antibody","description":"\u003cp\u003e\u003cb\u003eBackground\u003c\/b\u003e\u003c\/p\u003e\u003cp\u003eGAPDH encodes a member of the glyceraldehyde-3-phosphate dehydrogenase protein family. Glyceraldehyde-3-phosphate dehydrogenase has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. The product of GAPDH catalyzes an important energy-yielding step in carbohydrate metabolism, the reversible oxidative phosphorylation of glyceraldehyde-3-phosphate in the presence of inorganic phosphate and nicotinamide adenine dinucleotide (NAD). Glyceraldehyde-3-phosphate dehydrogenase has additionally been identified to have uracil DNA glycosylase activity in the nucleus. Also, Glyceraldehyde-3-phosphate dehydrogenase contains a peptide that has antimicrobial activity against E. coli, P. aeruginosa, and C. albicans. Studies of a similar protein in mouse have assigned a variety of additional functions including nitrosylation of nuclear proteins, the regulation of mRNA stability, and acting as a transferrin receptor on the cell surface of macrophage. Many pseudogenes similar to this locus are present in the human genome. Alternative splicing results in multiple transcript variants.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eOthers\u003c\/b\u003e\u003c\/p\u003e\u003cp\u003eThe antibody detects endogenous GAPDH protein.\u003c\/p\u003e","brand":"Abbkine Scientific Co., Ltd.","offers":[{"title":"50 uL","offer_id":52901278024045,"sku":"ABL1021-50UL","price":79.0,"currency_code":"USD","in_stock":true},{"title":"200 uL","offer_id":52901278056813,"sku":"ABL1021-200UL","price":229.0,"currency_code":"USD","in_stock":true},{"title":"200 uL×5","offer_id":52901278089581,"sku":"ABL1021-200ULX5","price":759.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/A01021.jpg?v=1769705370","url":"https:\/\/www.ebiohippo.com\/products\/anti-gapdh-rabbit-polyclonal-antibody-bha13715006","provider":"BioHippo","version":"1.0","type":"link"}