{"product_id":"anti-grk6-rabbit-monoclonal-antibody-bha21010337","title":"Anti-GRK6 Rabbit Monoclonal Antibody","description":"\u003cp\u003eBoster Bio Anti-GRK6 Rabbit Monoclonal Antibody catalog # M03623. Tested in WB application. This antibody reacts with Human, Mouse.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eProtein\u003c\/strong\u003e: T-cell surface glycoprotein CD3 zeta chain | \u003cstrong\u003eGene\u003c\/strong\u003e: Heat shock 70 kDa protein 4 | \u003cstrong\u003eTarget\u003c\/strong\u003e: GRK6 | \u003cstrong\u003eFunction\u003c\/strong\u003e: Mitochondrial membrane ATP synthase (F (1)F (0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F (1) - containing the extramembraneous catalytic core, and F (0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F (1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Subunits alpha and beta form the catalytic core in F (1). Rotation of the central stalk against the surrounding alpha (3)beta (3) subunits leads to hydrolysis of ATP in three separate catalytic sites on the beta subunits. Subunit alpha does not bear the catalytic high-affinity ATP-binding sites (By similarity). . | \u003cstrong\u003eResearch areas\u003c\/strong\u003e: Cell Biology,Chaperones,Heat Shock Proteins,Metabolism,Oxidative Stress,Pathways and Processes,Protein Trafficking,Redox Metabolism,Signal Transduction\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eHost\u003c\/strong\u003e: Rabbit | \u003cstrong\u003eClonality\/Clone\u003c\/strong\u003e: Monoclonal \/ Clone: 28G47 | \u003cstrong\u003eIsotype\u003c\/strong\u003e: IgG | \u003cstrong\u003eReactivity\u003c\/strong\u003e: Human,Mouse | \u003cstrong\u003eImmunogen\u003c\/strong\u003e: A synthesized peptide derived from human GRK6 | \u003cstrong\u003eConcentration\u003c\/strong\u003e: 0.5mg\/ml | \u003cstrong\u003ePurification\u003c\/strong\u003e: Affinity-chromatography\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eApplications\u003c\/strong\u003e: WB\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eObserved MW\u003c\/strong\u003e: 66 kDa | \u003cstrong\u003eCalculated MW\u003c\/strong\u003e: 94331 MW\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eCellular localization\u003c\/strong\u003e: Cytoplasm .\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eTissue details\u003c\/strong\u003e: Fetal lung, heart, liver, gut and kidney. Expressed at higher levels in the fetal brain, retina and spinal cord. .\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eStatus\u003c\/strong\u003e: Active\u003c\/p\u003e","brand":"Boster Bio","offers":[{"title":"100 uL\/vial \/ Unconjugated","offer_id":53072123986285,"sku":"M03623","price":370.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/m03623-wb.jpg?v=1772621953","url":"https:\/\/www.ebiohippo.com\/products\/anti-grk6-rabbit-monoclonal-antibody-bha21010337","provider":"BioHippo","version":"1.0","type":"link"}