{"product_id":"anti-histone-h3-formyl-k122-rabbit-monoclonal-antibody-bha21010200","title":"Anti-Histone H3 (formyl K122) Rabbit Monoclonal Antibody","description":"\u003cp\u003eBoster Bio Anti-Histone H3 (formyl K122) Rabbit Monoclonal Antibody catalog # M12477-16. Tested in WB, IHC applications. This antibody reacts with Human, Mouse, Rat.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eProtein\u003c\/strong\u003e: T-cell surface glycoprotein CD3 zeta chain | \u003cstrong\u003eGene\u003c\/strong\u003e: Histone H3.1 | \u003cstrong\u003eTarget\u003c\/strong\u003e: H3C1 | \u003cstrong\u003eFunction\u003c\/strong\u003e: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. | \u003cstrong\u003eResearch areas\u003c\/strong\u003e: 2339,Epigenetics and Nuclear Signaling,Histones,Unmodified\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eHost\u003c\/strong\u003e: Rabbit | \u003cstrong\u003eClonality\/Clone\u003c\/strong\u003e: Monoclonal \/ Clone: 27H08 | \u003cstrong\u003eIsotype\u003c\/strong\u003e: IgG | \u003cstrong\u003eReactivity\u003c\/strong\u003e: Human,Mouse,Rat | \u003cstrong\u003eImmunogen\u003c\/strong\u003e: A synthesized peptide derived from human Histone H3 (formyl K122) | \u003cstrong\u003eConcentration\u003c\/strong\u003e: 0.5mg\/ml | \u003cstrong\u003ePurification\u003c\/strong\u003e: Affinity-chromatography\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eApplications\u003c\/strong\u003e: WB, IHC\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eObserved MW\u003c\/strong\u003e: 15 kDa | \u003cstrong\u003eCalculated MW\u003c\/strong\u003e: 15 kDa\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eCellular localization\u003c\/strong\u003e: Nucleus. Chromosome.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eTissue details\u003c\/strong\u003e: Highly expressed in the brain, with higher expression during development than in adult. Expressed also in mammary glands, testis, colon and kidney. .\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eStatus\u003c\/strong\u003e: Active\u003c\/p\u003e","brand":"Boster Bio","offers":[{"title":"100 uL\/vial \/ Unconjugated","offer_id":53072120709485,"sku":"M12477-16","price":370.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/m12477-16-wb.jpg?v=1772621947","url":"https:\/\/www.ebiohippo.com\/products\/anti-histone-h3-formyl-k122-rabbit-monoclonal-antibody-bha21010200","provider":"BioHippo","version":"1.0","type":"link"}